ArticleNPJ systems biology and applications2026
Multiscale hyperbolic embedding reveals hierarchical structure in complex biological systems.
Article in NPJ systems biology and applications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The rapid expansion of biological and computational datasets demands scalable methods that support both visualization and quantitative interpretation. Hyperbolic embeddings are well-suited to represent hierarchical structure, but existing approaches are limited by fixed curvature assumptions or poor scalability to large datasets. We introduce MuH-MDS, a multiscale hyperbolic multidimensional scaling algorithm that employs an adiabatic optimization strategy: local positions are iteratively refined while cluster centroids are temporarily fixed. This strategy accelerates computation by 10
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