Evidence map›Paper›PMID 42230498›Full record

ArticleBulletin of experimental biology and medicine2026

Blood Plasma Cytokine Concentration in Female Rats with Temporomandibular Joint Osteoarthritis.

V D Vinnikova, O S Pak, I V Vorozhko, T N Korotkova, A V Klimenko, A Yu Abramova, S S Pertsov

Abstract read
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In one paragraph

Article in Bulletin of experimental biology and medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

V D VinnikovaFederal Research Center for Innovator and Emerging Biomedical and Pharmaceutical Technologies, Moscow, Russia. vinnikova_vd@academpharm.ru.
O S PakFederal Research Center for Innovator and Emerging Biomedical and Pharmaceutical Technologies, Moscow, Russia.
I V VorozhkoFederal Research Centre of Nutrition, Biotechnology and Food Safety, Moscow, Russia.
T N KorotkovaFederal Research Centre of Nutrition, Biotechnology and Food Safety, Moscow, Russia.
A V KlimenkoFederal Research Center for Innovator and Emerging Biomedical and Pharmaceutical Technologies, Moscow, Russia.
A Yu AbramovaFederal Research Center for Innovator and Emerging Biomedical and Pharmaceutical Technologies, Moscow, Russia.
S S PertsovFederal Research Center for Innovator and Emerging Biomedical and Pharmaceutical Technologies, Moscow, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plasma concentrations of some cytokines were analyzed in female rats at different time points (on days 14 and 28) after induction of temporomandibular joint osteoarthritis via injection of sodium monoiodoacetate. Under these conditions, the concentrations of IL-6 and IL-10 in animals with temporomandibular joint dysfunction were lower than in intact animals at both the relatively early (day 14) and late (day 28) stages of observation. The level of TNFα in rats with experimental arthritis at the later stage of the study was higher than at the early stage. The observed changes may reflect a compensatory adjustment of immune mechanisms aimed at limiting the inflammatory response at different stages of its development.

Indexed as

Interleukin-10Interleukin-6OsteoarthritisTemporomandibular JointTemporomandibular Joint DisordersAnimalsCytokinesFemaleIodoacetic AcidRatsRats, WistarTumor Necrosis Factor-alphaCytokinesIl6 protein, ratInterleukin-10Interleukin-6Iodoacetic AcidTumor Necrosis Factor-alphafemale rats; temporomandibular joint osteoarthritis; blood cytokines

Identifiers

PMID42230498

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.