Evidence map›Paper›PMID 42230304›Full record

ArticleEmerging infectious diseases2026

Role of Households with Children in Community Spread of Multidrug-Resistant Enterobacterales, St. Louis, Missouri, USA.

Barrett Breeze, Ahmed Babiker, Sreenivas Konda, Alaina L Robinson, Stefan J Green, Catherine C Babbs, Federico Cunha, Katherine Y Shen, India Shepherd Hammond, Stephanie A Fritz and 1 more

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Barrett Breeze
Ahmed Babiker
Sreenivas Konda
Alaina L Robinson
Stefan J Green
Catherine C Babbs
Federico Cunha
Katherine Y Shen
India Shepherd Hammond
Stephanie A Fritz
Latania K Logan

Funding

Antibacterial Resistance Leadership Group (ARLG)UM1AI104681 · NIAID · DUKE UNIVERSITY · PI Vance G. Fowler, Henry F HENRY CHAMBERS · 2013 to 2026
$180.8M
Households as Reservoirs of Community-Acquired Extended-Spectrum Beta-Lactamase-producing EnterobacteralesR21AI173471 · NIAID · EMORY UNIVERSITY · PI LOGAN, LATANIA K. · 2023 to 2024
$452k
NIAID NIH HHS R21 AI173471NIAID NIH HHS UM1 AI104681
6 · The paper itself

Abstract

Community-acquired multidrug-resistant (MDR) Enterobacterales bacteria are an increasing public health concern, yet whether households play a role in community spread remains unclear. We investigated 150 households with children in St. Louis, Missouri, USA, for MDR Enterobacterales. We cultured swab specimens from household members and environmental surfaces for identification and antimicrobial susceptibility testing. We also performed whole-genome sequencing in the 53 (35%) households where >1 MDR Enterobacterales species were recovered. Enterobacter hormaechei predominated, followed by Klebsiella pneumoniae and Pantoea species. Whole-genome sequencing revealed closely related strains shared between persons and environmental surfaces, suggesting potential intra-household transmission. We identified >1 horizontal gene transfer event between Enterobacterales genera within a household. On multivariable analysis, households that had children attending daycare, a member with an ADHD diagnosis, and dog ownership were associated with increased odds of household MDR Enterobacterales colonization. Households likely serve as major contributors in acquisition and community spread of MDR Enterobacterales.

Indexed as

Community-Acquired InfectionsDrug Resistance, Multiple, BacterialEnterobacteriaceaeEnterobacteriaceae InfectionsFamily CharacteristicsAnimalsAnti-Bacterial AgentsChildChild, PreschoolFemaleHumansMaleMicrobial Sensitivity TestsMissouriWhole Genome SequencingAnti-Bacterial Agentsantibiotic resistanceantimicrobial resistancebacteriabacterial infectionsbeta-lactamaseschildrencommunityEnterobacteralesepidemiologyUnited States

Identifiers

PMID42230304
PMCPMC13245223

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.