Evidence map›Paper›PMID 42230285›Full record

ArticleEmerging infectious diseases2026

Characteristics of Plausible Source Cases Responsible for Recent Mycobacterium tuberculosis Transmission, United States, 2018-2022.

Steve Kammerer, Daniel Flanagan, Kala Raz, Tambi Shaw, Jonathan Wortham, Sarah Talarico

Abstract readHistorical Article
In one paragraph

Article in Emerging infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Steve Kammerer
Daniel Flanagan
Kala Raz
Tambi Shaw
Jonathan Wortham
Sarah Talarico

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis (TB) outbreaks in the United States can cause substantial illness. Using surveillance and genotyping data, we applied a plausible source-case algorithm to identify TB cases reported during 2018-2020 responsible for secondary cases attributed to recent Mycobacterium tuberculosis transmission during 2020-2022. We used mixed models and a machine learning workflow to assess sociodemographic, clinical, and social risk factors associated with plausible sources. In mixed models, sputum smear positivity, cavitary disease, race/ethnicity other than non-Hispanic White or non-Hispanic Asian, age <65 years, US birth, and homelessness were associated with plausible sources. An adaptive boosting model achieved an area under the receiver operating characteristic curve of 0.81 on test data. Transmission was heterogeneous; 8.1% of sources linked to 3-15 secondary cases accounted for 24.9% of transmission events. Focusing case management and contact investigations on cases with the characteristics we identified could reduce M. tuberculosis transmission and improve TB prevention.

Indexed as

Mycobacterium tuberculosisTuberculosisDisease OutbreaksFemaleHumansRisk FactorsUnited Statesbacteriadisease transmissioninfectiousmachine learningmolecular epidemiologyMycobacterium tuberculosispublic health surveillancerespiratory infectionssocial determinants of healthTBTuberculosis and other mycobacteriaUnited Stateswhole-genome sequencing

Identifiers

PMID42230285
PMCPMC13245205

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.