Evidence map›Paper›PMID 42230275›Full record

ReviewEmerging infectious diseases2026

Public Health Response to Toxigenic Respiratory Diphtheria Outbreaks at Correctional Facility, South Africa, 2023-2025.

Maria Jose, Nectarios Papavarnavas, Arifa Parker, Charlene Lawrence, Janine Bezuidenhout, Levani Naidoo, Yolanda Cottee, Kathryn Grammer, Wentzel Dowling, Jocelyn Moyes and 3 more

Abstract readReview
In one paragraph

Review in Emerging infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Maria Jose
Nectarios Papavarnavas
Arifa Parker
Charlene Lawrence
Janine Bezuidenhout
Levani Naidoo
Yolanda Cottee
Kathryn Grammer
Wentzel Dowling
Jocelyn Moyes
Anne von Gottberg
Mignon du Plessis
Hassan Mahomed

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since 2023, there have been 3 outbreaks of toxigenic respiratory diphtheria at a correctional facility in Cape Town, South Africa. The first outbreak in October 2023 included 1 fatal case and 8 asymptomatic carriers testing positive for Corynebacterium diphtheriae. In December 2024, the second outbreak resulted in 1 case and 12 asymptomatic carriers. A third outbreak in February 2025, occurring 6 weeks after the second, resulted in 1 case and 14 asymptomatic carriers among inmates and staff. Contact tracing, antimicrobial prophylaxis, and vaccination campaigns were conducted with each outbreak. We outline public health responses to the 3 outbreaks and highlight key barriers and enablers for effective control in a highly mobile, densely populated correctional setting. Effective outbreak response in correctional facilities requires intersectoral collaboration and the development of adult vaccination guidelines for staff and inmates to prevent future vaccine-preventable disease outbreaks.

Indexed as

Corynebacterium diphtheriaeDiphtheriaDisease OutbreaksPrisonsPublic HealthRespiratory Tract InfectionsContact TracingHumansSouth AfricaVaccinationadult vaccinesbacteriacarceral healthcongregate settingcorrectional facilityCorynebacterium diphtheriaediphtheriaoutbreakpublic healthrespiratory infectionsSouth Africatoxigenicvaccine hesitancy

Identifiers

PMID42230275
PMCPMC13245251

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.