Evidence map›Paper›PMID 42230142›Full record

ArticleBMJ open ophthalmology2026

Validation of 3nethra specto, a wearable digital subjective refractor versus conventional subjective refraction for refractive error measurement in young adults: a comparative study.

Kaushik Murali, Namratha Hegde, Afia S, Varshini M, Disha Agarwal, Revathy Manthri Rangaraj, Rashmi Hullur, Kousar Sidiq, Venkatakrishnan S

Abstract readComparative StudyValidation Study
In one paragraph

Article in BMJ open ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Kaushik MuraliDepartment of Paediatric Ophthalmology and Strabismus, Sankara Eye Hospital, Sankara Academy of Vision, Sankara Eye Foundation India, Bengaluru, Karnataka, India.ORCID http://orcid.org/0000-0002-1385-3227
Namratha HegdeSankara Academy of Vision, Sankara Eye Foundation India, Bengaluru, Karnataka, India namratha.hegde@gmail.com.ORCID http://orcid.org/0000-0002-6787-7830
Afia SSankara College of Optometry, Sankara Academy of Vision, Bengaluru, Karnataka, India.ORCID http://orcid.org/0009-0009-3279-7601
Varshini MSankara College of Optometry, Sankara Academy of Vision, Bengaluru, Karnataka, India.ORCID http://orcid.org/0009-0007-6995-0169
Disha AgarwalDepartment of Paediatric Ophthalmology and Strabismus, Sankara Eye Hospital, Sankara Academy of Vision, Sankara Eye Foundation India, Bengaluru, Karnataka, India.ORCID http://orcid.org/0009-0001-8272-2749
Revathy Manthri RangarajResearch and Development, Forus Health Pvt Ltd, Bangalore, Karnataka, India.ORCID http://orcid.org/0009-0002-3240-8839
Rashmi HullurResearch and Development, Forus Health Pvt Ltd, Bangalore, Karnataka, India.ORCID http://orcid.org/0009-0006-3249-4254
Kousar SidiqResearch and Development, Forus Health Pvt Ltd, Bangalore, Karnataka, India.ORCID http://orcid.org/0009-0002-6400-4839
Venkatakrishnan SResearch and Development, Forus Health Pvt Ltd, Bangalore, Karnataka, India.ORCID http://orcid.org/0009-0006-2783-6475

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRefractive errors cause significant preventable visual impairment globally, particularly in underserved areas. Conventional subjective refraction remains the gold standard but proves examiner-dependent, time-consuming and challenging in high-volume settings. The 3nethra Specto, a wearable digital subjective refractometer, offers rapid refractive assessment. This study evaluates its accuracy and repeatability versus conventional methods.

methodsA prospective comparative study was conducted on 135 subjects who underwent both conventional subjective refraction and 3nethra Specto assessment. Spherical (S), cylindrical (C) and axis measurements were analysed using power vector transformation (J₀, J₄₅). Primary predictive validity was assessed using univariate general linear models (GLMs) (IBM SPSS V.25.0) with age/sex as covariates. Model fit was evaluated via F-statistics, R² and residual SD. Instrument repeatability used GLM Repeated Measures, agreement assessed via Bland-Altman plots, keeping significance at p<0.05. Patient and examiner feedback on the instrument was captured using the User Experience questionnaire.

resultsOf 135 adults (mean age 31.5±8.9 years; 60% male), compound myopic astigmatism predominated (45%). 3nethra Specto measurements closely matched subjective refraction (sphere: -1.02 D vs -0.99 D; cylinder: -0.49 D vs -0.83 D; M: -1.26 D vs -1.24 D). GLM analysis showed excellent predictive validity (all p<0.001; R² 0.914 to 0.994; residual SD 0.084 D to 0.228 D). Bland-Altman plots confirmed 95% limits of agreement of -0.39 D to +0.47 D for M and -0.62 D to +0.64 D for J₀ and -0.32 D to +0.35 D for J₄₅. Device repeatability was high (all F>96, p<0.001; R²≥0.956; residual SD≤0.148 D). Patients rated subjective refraction higher for comfort/enjoyability but found 3nethra more inventive/exciting; examiners preferred 3nethra for efficiency, speed, innovation and ease of use.

conclusionsThe 3nethra Specto wearable liquid lens refractor demonstrated excellent agreement and repeatability with traditional subjective refraction across all refractive parameters, confirming clinical equivalence. Positive patient and examiner feedback highlighted its innovation, efficiency and usability. This device offers a reliable alternative for routine refractive assessment in clinical settings.

Indexed as

Refraction, OcularRefractive ErrorsRefractometryVision TestsWearable Electronic DevicesAdultEquipment DesignFemaleHumansMaleProspective StudiesReproducibility of ResultsYoung AdultOptics and RefractionSmartphoneTelemedicineVision

Identifiers

PMID42230142
PMCPMC13239662

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.