ArticlePloS one2026
Hepatitis B vaccine uptake and associated factors among pregnant women attending antenatal care at Gulu Regional Referral Hospital, Northern Uganda.
Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundHepatitis B virus (HBV) infection is a global public health concern. Uganda has a high prevalence of HBV infection among pregnant mothers. This study aimed to determine HBV vaccine uptake and associated factors among pregnant women attending Antenatal Care (ANC) at Gulu Regional Referral Hospital (GRRH).
methodsThis was a cross-sectional study. Data were collected from 430 participants who were selected by systematic sampling. Data were collected using an electronic questionnaire built on the Kobo Collect server and analyzed using STATA version 16.0. Prevalence ratios (PR) were calculated using a modified Poisson regression analysis to determine the association between HBV vaccine uptake and the predictors.
resultsMore than half (53%:229/430) of the pregnant mothers had received at least a dose of the HBV vaccine. Factors statistically significantly associated with HBV vaccine uptake included age (APR = 1.10, 95% CI: 1.02-1.18), knowledge about HBV (APR = 1.06, 95% CI: 1.01-1.10), and healthcare worker communication (APR = 1.17, 95% CI: 1.04-1.32).
conclusionMore than half of pregnant mothers had received at least a dose of the HBV vaccination. Age, knowledge, and healthcare communication influenced vaccine uptake. There is a need to provide adequate health education regarding the importance of completing the HBV vaccine to pregnant women and community members to improve vaccine outcomes.
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