Evidence map›Paper›PMID 42228712›Full record

ArticlePloS one2026

Can immersive virtual reality magnify treatment outcomes of computerized script training on Cantonese speakers with chronic aphasia? Protocol of a randomized controlled trial.

Winsy Wing Sze Wong, Donald Shi Pui Li, Kenneth Ngai Kuen Fong, Peter Hiu Fung Ng, Hoi Tsz Karen Kwok

Erratum issued Registry-linked trialAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT06722092 (Can Immersive Virtual Reality Magnify Treatment Outcomes of Script Training on Cantonese Speakers with Chronic Aphasia), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06722092 nanot yet recruitingnot on this map

Can Immersive Virtual Reality Magnify Treatment Outcomes of Script Training on Cantonese Speakers with Chronic Aphasia: a Randomized Controlled Trial

TypeinterventionalSponsorThe Hong Kong Polytechnic UniversityRan2025 to 2028Enrolled105ConditionsAphasia, Acquired, Chronic StrokeArmsVR-based script training, Conventional script training
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Winsy Wing Sze WongDepartment of Language Science and Technology, Faculty of Humanities, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR, China.ORCID https://orcid.org/0000-0003-0420-2964
Donald Shi Pui LiDepartment of Cognitive Science, Krieger School of Arts and Sciences, Johns Hopkins University, Baltimore, Maryland, United States of America.
Kenneth Ngai Kuen FongDepartment of Rehabilitation Sciences, Faculty of Health and Social Sciences, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR, China.
Peter Hiu Fung NgDepartment of Computing, Faculty of Engineering, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR, China.
Hoi Tsz Karen KwokDepartment of Language Science and Technology, Faculty of Humanities, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR, China.ORCID https://orcid.org/0000-0002-0834-9480

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAphasia persists in 20% of the stroke population. Speech therapy has been suggested to benefit the functional communication of people with aphasia (PWA). Virtual reality (VR) has been widely applied in motor/cognitive rehabilitation of stroke patients. The current proposal investigates the efficacy of VR-based computerized script training on the functional communication of PWA.

methodsA three-armed assessor-blinded randomized controlled trial (RCT) will recruit 120 PWA. They will be randomly assigned to 1) VR-based computerized script training, 2) computerized script training without VR, or 3) no treatment control. In the VR condition, PWA will practice in VR depicting everyday contexts, while in the non-VR group, PWA will practice with static photos. PWA in the control group will be assessed without training. Outcomes on functional communication, aphasia severity, and quality of life will be compared before/after treatment. The findings will provide empirical evidence to inform the development of effective and ecologically valid interventions for PWA.

trial registrationClinicalTrials.gov NCT06722092.

Indexed as

AphasiaSpeech TherapyStroke RehabilitationVirtual RealityAdultAgedChronic DiseaseFemaleHumansMaleMiddle AgedQuality of LifeRandomized Controlled Trials as TopicStrokeTreatment Outcome

Identifiers

PMID42228712
PMCPMC13229358

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.