Evidence map›Paper›PMID 42228528›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

A 3'UTR-derived small RNA modulates the life cycle of the cholera toxin-encoding filamentous phage, CTXϕ.

Anne Lippegaus, James R J Haycocks, Eoghan O'Driscoll, Marcel Sprenger, Kerstin Thriene, Elke-Martina Jung, Malte Siemers, Sebastian Krautwurst, David C Grainger, Kai Papenfort

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Prophage-Derived Molecules as Anti-Antibiotics (Basel, Switzerland) · 2026
    Review
  2. Bacterial small regulatory RNAs.Nature reviews. Microbiology · 2026
    Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Anne LippegausInstitute of Microbiology, General Microbiology, Friedrich Schiller University, Jena 07743, Germany.ORCID 0000-0001-8492-1947
James R J HaycocksInstitute of Microbiology and Infection, School of Biosciences, University of Birmingham, Birmingham B15 2TT, United Kingdom.
Eoghan O'DriscollInstitute of Microbiology, General Microbiology, Friedrich Schiller University, Jena 07743, Germany.
Marcel SprengerInstitute of Microbiology, General Microbiology, Friedrich Schiller University, Jena 07743, Germany.ORCID 0000-0002-8757-1230
Kerstin ThrieneInstitute of Microbiology, General Microbiology, Friedrich Schiller University, Jena 07743, Germany.
Elke-Martina JungInstitute of Microbiology, General Microbiology, Friedrich Schiller University, Jena 07743, Germany.
Malte SiemersInstitute of Microbiology, General Microbiology, Friedrich Schiller University, Jena 07743, Germany.
Sebastian KrautwurstInstitute of Microbiology, General Microbiology, Friedrich Schiller University, Jena 07743, Germany.ORCID 0000-0002-9413-5701
David C GraingerInstitute of Microbiology and Infection, School of Biosciences, University of Birmingham, Birmingham B15 2TT, United Kingdom.
Kai PapenfortInstitute of Microbiology, General Microbiology, Friedrich Schiller University, Jena 07743, Germany.ORCID 0000-0002-5560-9804

Funding

Deutsche Forschungsgemeinschaft (DFG) CRC1127-3 - Project-ID 239748522Deutsche Forschungsgemeinschaft (DFG) EXC 2051 - Project-ID 390713860EC | Horizon Europe | Excellent Science | HORIZON EUROPE European Research Council (ERC) CoG-101088027
6 · The paper itself

Abstract

Bacteriophages (phages) are well known to be one of the major driving forces in bacterial evolution. This also applies to virulent microorganisms, such as the major human pathogen

Indexed as

3' Untranslated RegionsInovirusRNA, Small UntranslatedVibrio choleraeCholera ToxinGene Expression Regulation, BacterialGenome, ViralLife Cycle Stages3' Untranslated RegionsCholera ToxinRNA, Small UntranslatedCTXϕ phageHfqRIL-seqsmall RNAVibrio cholerae

Identifiers

PMID42228528
PMCPMC13250501

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.