Evidence map›Paper›PMID 42228406›Full record

ReviewEmerging infectious diseases2026

Outbreak of Legionnaires' Disease Linked to Newly Installed Residential Water Heaters, the Netherlands, 2022-2023.

Daphne F M Reukers, Sjoerd M Euser, Alvin A Bartels, Martijn G Keet, Marijke Boot, Wilhelmina L M Ruijs, Petra S Brandsema

Abstract readReview
In one paragraph

Review in Emerging infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Daphne F M Reukers
Sjoerd M Euser
Alvin A Bartels
Martijn G Keet
Marijke Boot
Wilhelmina L M Ruijs
Petra S Brandsema

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During 2022-2023, two small Legionnaires' disease (LD) clusters (2 and 4 cases) occurred in 2 residential apartment buildings in the Netherlands. All case-patients recently installed a new brand A water heater. Environmental sampling revealed Legionella pneumophila serogroup 1 sequence type 37 in the hot water system of each case-patient's apartment, matching 1 clinical isolate. We conducted a case-control study to evaluate whether brand A water heaters were linked to cases in the 2 clusters. We identified 23 LD case-patients, 21 of whom had a brand A water heater installed <6 months before illness onset. Four cases had a genotypic match between clinical and environmental isolates; none of 31 control-patients had recently installed a water heater. Analyses showed that LD cases were strongly associated with new brand A water heaters (OR 542 [95% CI 24.76-11,854.03]); the manufacturer implemented control measures. Residential water heaters could serve as L. pneumophila transmission sources.

Indexed as

Disease OutbreaksHeatingLegionella pneumophilaLegionnaires' DiseaseWater MicrobiologyAdultAgedAged, 80 and overCase-Control StudiesFemaleHumansMaleMiddle AgedNetherlandsbacteriaLegionella pneumophilaLegionnaire’s diseaseoutbreakprivate homesrespiratory infectionsthe Netherlandswater heaterwater system

Identifiers

PMID42228406
PMCPMC13322443

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.