Evidence map›Paper›PMID 42228299›Full record

ArticleInternational journal of clinical oncology2026

Fibroblast activation protein inhibitor-PET/CT in lung cancer: a prospective single-center study with histopathological correlation of fibroblast activation protein expression.

Takashi Hiroshima, Toru Kimura, Tadashi Watabe, Takahiro Matsui, Akiisa Omura, Yusuke Sugiura, Hideki Nagata, Kenji Kimura, Eriko Fukui, Takashi Kanou and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of clinical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Takashi HiroshimaDepartment of General Thoracic Surgery, The University of Osaka Graduate School of Medicine, Suita, Japan.
Toru KimuraDepartment of General Thoracic Surgery, The University of Osaka Graduate School of Medicine, Suita, Japan. kimura@thoracic.med.osaka-u.ac.jp.ORCID http://orcid.org/0000-0003-4504-232X
Tadashi WatabeDivision of Clinical Translation, Department of General Thoracic Surgery Institute for Radiation Sciences, The University of Osaka Graduate School of Medicine, Suita, Japan.
Takahiro MatsuiDepartment of Pathology, The University of Osaka Graduate School of Medicine, Suita, Japan.
Akiisa OmuraDepartment of General Thoracic Surgery, The University of Osaka Graduate School of Medicine, Suita, Japan.
Yusuke SugiuraDepartment of General Thoracic Surgery, The University of Osaka Graduate School of Medicine, Suita, Japan.
Hideki NagataDepartment of General Thoracic Surgery, The University of Osaka Graduate School of Medicine, Suita, Japan.
Kenji KimuraDepartment of General Thoracic Surgery, The University of Osaka Graduate School of Medicine, Suita, Japan.
Eriko FukuiDepartment of General Thoracic Surgery, The University of Osaka Graduate School of Medicine, Suita, Japan.
Takashi KanouDepartment of General Thoracic Surgery, The University of Osaka Graduate School of Medicine, Suita, Japan.
Naoko OseDepartment of General Thoracic Surgery, The University of Osaka Graduate School of Medicine, Suita, Japan.
Mitsuaki TatsumiDepartment of Diagnostic Radiology, Faculty of Medicine, Juntendo University, Tokyo, Japan.
Frederik L GieselDivision of Clinical Translation, Department of General Thoracic Surgery Institute for Radiation Sciences, The University of Osaka Graduate School of Medicine, Suita, Japan.
Eiichi MoriiDepartment of Pathology, The University of Osaka Graduate School of Medicine, Suita, Japan.
Yasushi ShintaniDepartment of General Thoracic Surgery, The University of Osaka Graduate School of Medicine, Suita, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent studies have demonstrated the utility of fibroblast activation protein inhibitor (FAPI)-positron emission tomography (PET) for cancer diagnosis. We investigated the diagnostic capability of [

methodsThis study included 30 patients (June 2022 to February 2024) who underwent [

resultsAll 30 primary lung lesions showed uptake on [

conclusionsIn resectable early-stage lung cancer, [

Indexed as

GelatinasesLung NeoplasmsMembrane ProteinsPositron Emission Tomography Computed TomographySerine EndopeptidasesAdultAgedAged, 80 and overEndopeptidasesFemaleFibroblast Activation Protein AlphaHumansLymphatic MetastasisMaleMiddle AgedProspective StudiesEndopeptidasesFibroblast Activation Protein AlphaGelatinasesMembrane ProteinsSerine Endopeptidases[18F]FAPI-74 PETCancer-associated fibroblastsFibroblast activation proteinLung cancerLymph node metastasis

Identifiers

PMID42228299
PMCPMC13303691

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.