Evidence map›Paper›PMID 42228216›Full record

ArticlePlant molecular biology2026

Genome-wide association studies reveal a functional SNP and candidate genes associated with alkali tolerance in alfalfa.

Chunxia Zhang, Jinhuan Sun, Zhibin Fan, Qixiumei He, Yuci Hu, Kezhen Yang, Jie Le

Abstract read
PubMed Publisher
In one paragraph

Article in Plant molecular biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chunxia Zhang *Key Laboratory of Plant Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, Beijing, 100093, China.ORCID http://orcid.org/0000-0001-8525-8868
Jinhuan Sun *Key Laboratory of Plant Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, Beijing, 100093, China.
Zhibin Fan *Key Laboratory of Plant Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, Beijing, 100093, China.
Qixiumei HeKey Laboratory of Plant Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, Beijing, 100093, China.
Yuci HuKey Laboratory of Plant Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, Beijing, 100093, China.
Kezhen YangKey Laboratory of Plant Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, Beijing, 100093, China.
Jie LeKey Laboratory of Plant Molecular Physiology, Institute of Botany, Chinese Academy of Sciences, Beijing, 100093, China. lejie@ibcas.ac.cn.ORCID http://orcid.org/0000-0001-8854-3031

Funding

Institute of Engineering Thermophysics, Chinese Academy of Sciences XDA26030102 and XDB1290000the National Natural Science Foundation of China 32070723the National Natural Science Foundation of China 32300302
6 · The paper itself

Abstract

Alfalfa (Medicago sativa L.), the world's most widely cultivated perennial forage crop, is valued for its high-quality feed and broad environmental adaptability. However, soil alkalization poses a major constraint to its productivity in marginal lands, with the genetic basis of alkali tolerance remaining largely unexplored. This study identified a lead SNP (Chr7-16,804,032) via a genome-wide association study (GWAS), where the T/T genotype was strongly associated with enhanced alkali tolerance. Physiological analyses revealed that lines carrying the T/T genotype maintained higher chlorophyll and soluble protein content, lower malondialdehyde levels, elevated antioxidant enzyme activities, and better Na

Indexed as

AlkaliesGenes, PlantGenome-Wide Association StudyMedicago sativaPolymorphism, Single NucleotideArabidopsisGene Expression Regulation, PlantGenotypePlant ProteinsStress, PhysiologicalAlkaliesPlant ProteinsAlfalfaAlkali stressFunctional validationGenome-wide association study (GWAS)GenotypeSNP

Identifiers

PMID42228216

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.