ArticleCalcified tissue international2026
Protrusio Acetabuli in Osteogenesis Imperfecta: A Two-Center Study on Incidence and Associated Factors.
Article in Calcified tissue international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Osteogenesis imperfecta (OI) is a rare genetic connective tissue disorder characterized by increased fracture risk and bone deformity. Protrusio acetabuli (PA) is a well-recognized radiographic finding in patients with OI, yet data on its incidence, severity, and associated factors across different OI phenotypes remain limited. This retrospective study evaluated pelvic radiographs and clinical data of patients with OI treated in two centers. PA was assessed using established radiographic criteria and graded according to the Sotelo-Garza/Charnley classification. Demographic and clinical variables were analyzed to identify factors associated with PA. Of 69 patients included, PA was found in 32 (46.4%), of whom nine presented with severe, 15 with moderate, and eight with mild PA. Patients with PA were significantly older than those without PA. Univariable logistic regression identified female sex, body mass index > 25 kg/m
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