Evidence map›Paper›PMID 42228178›Full record

SynthesisEuropean journal of nutrition2026

Effects of green tea use on the metabolic profile of postmenopausal women: systematic review and meta-analysis.

Isabella Heloísa Rodrigues Zago, Laura Colonetti, Eduarda Letícia Balbinot, Igor Specht Taschetto, Antonio José Grande, Maria Inês da Rosa, Tamy Colonetti

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in European journal of nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Isabella Heloísa Rodrigues ZagoSchool of Medicine, Universidade do Extremo Sul Catarinense (UNESC), Criciúma, SC, Brazil.
Laura ColonettiLaboratory of Translational Biomedicine, Universidade do Extremo Sul Catarinense, Criciúma, SC, Brazil.
Eduarda Letícia BalbinotSchool of Medicine, Universidade do Extremo Sul Catarinense (UNESC), Criciúma, SC, Brazil.
Igor Specht TaschettoSchool of Medicine, Universidade do Extremo Sul Catarinense (UNESC), Criciúma, SC, Brazil.
Antonio José GrandeLaboratory of evidence-based practice, Universidade Estadual de Mato Grosso do Sul, Campo Grande, MS, Brazil.
Maria Inês da RosaLaboratory of Translational Biomedicine, Universidade do Extremo Sul Catarinense, Criciúma, SC, Brazil.
Tamy ColonettiSchool of Medicine, Universidade do Extremo Sul Catarinense (UNESC), Criciúma, SC, Brazil. tamycolonetti@unesc.net.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAmong the main consequences of menopause are changes in body weight, lipid and metabolic profiles, as well as an increased risk of cardiovascular disease. This study aimed to analyze the effects of green tea consumption on the metabolic profile of postmenopausal women.

methodsThis is a systematic review of randomized controlled trials (RCTs) evaluating the effects of green tea compared with placebo in postmenopausal women. The search was conducted in the following electronic databases: MEDLINE via PubMed, EMBASE via Elsevier, the Cochrane Library, LILACS via BVS, and Web of Science, using the terms "Tea," "Green tea extract," "Metabolic profile", "Menopause," and "Postmenopause" (MeSH descriptors and synonyms). The outcomes listed in the study protocol were: weight, body mass index (BMI), body composition, lipid profile, and blood glucose.

resultsData were collected from seven RCTs that met the selection criteria. The meta-analysis showed that green tea reduced total cholesterol levels in postmenopausal women (mean difference [MD]: -7.03; 95% confidence interval [CI]: -13.24 to - 0.82; p = 0.03; I² = 0%; four studies; 1,109 participants; low-quality evidence). However, no statistically significant effects were observed for the other evaluated outcomes.

conclusionThis meta-analysis demonstrated that green tea resulted in reductions in total cholesterol levels in postmenopausal women. However, further high-quality randomized controlled trials with standardized dosage, formulation, and duration are needed to confirm these findings and support the safe clinical use of green tea as an adjunctive strategy. High-dose concentrated extracts should be used with caution, and hepatic function monitoring may be warranted.

Indexed as

MetabolomePostmenopauseTeaBlood GlucoseBody CompositionBody Mass IndexCholesterolFemaleHumansMiddle AgedPlant ExtractsRandomized Controlled Trials as TopicBlood GlucoseCholesterolPlant ExtractsTeaGreen teaMetabolic syndromePostmenopause

Identifiers

PMID42228178
PMCPMC13230310

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.