Evidence map›Paper›PMID 42228140›Full record

ArticleVirchows Archiv : an international journal of pathology2026

Tissue biobanking: minimum interface requirements for efficient and high-quality support for biomedical research - a white paper.

Cäcilia Engels, Angela Langer, Britta Fritzsche, Carolin Kaufhold-Wedel, Christoph Brochhausen, Heidi Altmann, Julian Dörenberg, Katharina Hofmann, Michael Linnebacher, Nhu Tuyen Phan and 5 more

Abstract read
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In one paragraph

Article in Virchows Archiv : an international journal of pathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Cäcilia EngelsGerman Cancer Consortium (DKTK), partner site Berlin, a partnership between DKFZ and Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID http://orcid.org/0000-0003-1448-7190
Angela LangerAugsburg Central BioBank, Medical Faculty, University of Augsburg, Augsburg, Germany.
Britta FritzscheUniversity Cancer Center Hamburg, Universitätsklinikum Hamburg-Eppendorf (UKE), Hamburg, Germany.
Carolin Kaufhold-WedelTissue Bank of the National Center for Tumor Diseases (NCT) Heidelberg, Heidelberg, Germany.ORCID http://orcid.org/0000-0001-6730-2220
Christoph BrochhausenInstitute of Pathology, Medical Faculty Mannheim, University Medical Center Mannheim, Heidelberg University, Mannheim, Germany.
Heidi AltmannDresden Integrated Liquid Biobank/BioBank Dresden, Institute for Clinical Chemistry and Laboratory Medicine, Dresden, Germany.
Julian DörenbergCore Facility Biobank, Medical Faculty, University of Tübingen, Tübingen, Germany.ORCID http://orcid.org/0009-0003-8588-5804
Katharina HofmannBioMaterialBank Heidelberg (BMBH), Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.ORCID http://orcid.org/0000-0002-3610-5897
Michael LinnebacherBioBank Rostock, Clinic of General Surgery, Rostock University Medical Center, Rostock, Germany.ORCID http://orcid.org/0000-0001-8054-1402
Nhu Tuyen PhanGerman Biobank Network (GBN) Coordination Office, Network of University Medicine (NUM), Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID http://orcid.org/0000-0001-7919-5477
Ronny BaberLeipzig Medical Biobank (LMB) and Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Leipzig, Leipzig, Germany.ORCID http://orcid.org/0009-0004-2539-7849
Till BraunschweigBavarian Cancer Research Center (BZKF), Augsburg, Germany.ORCID http://orcid.org/0000-0001-9166-2912
Tilman PfefferTissue Bank of the German Center for Infection Research (DZIF), Partner Site Heidelberg, Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.ORCID http://orcid.org/0000-0003-1502-426X
Alexander BrobeilTissue Bank of the National Center for Tumor Diseases (NCT) Heidelberg, Heidelberg, Germany.
Katja SteigerBavarian Cancer Research Center (BZKF), Augsburg, Germany. katja.steiger@tum.de.ORCID http://orcid.org/0000-0002-7269-5433

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tissue biobanking is essential for biomedical research. Well-defined interfaces and standardised procedures are required to ensure sample quality and the subsequent reproducibility of research results. This paper provides an overview of the key interfaces involved in tissue biobanking workflows, including sample collection, processing, storage, distribution and data management. It outlines the minimum standards required to maintain high-quality samples and associated data, and references relevant national and international guidelines. The paper also addresses the current challenges faced by biobanks, such as harmonisation across institutions, evolving regulatory landscapes, and the integration of digital infrastructure. The primary aim of this work is to present recommendations for the effective implementation and documentation of minimum standards. These recommendations are intended to help biobanks to align with regulatory expectations, optimise operational procedures, and facilitate high-quality, ethically sound biomedical research.

Indexed as

BiobankingBiosamplesISO 20387Quality managementStandardisationTissue processing

Identifiers

PMID42228140

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.