Evidence map›Paper›PMID 42228133›Full record

ArticleArchives of toxicology2026

N-Ethylpentedrone: first hair detection and human metabolic profiling across multiple biological matrices using UHPLC-HRMS, molecular networking and in silico prediction.

Agathe Pasquet, Romain Pelletier, Roxane Rouah, Tania Panter, Mélanie Loiseau, François-Hugues Porée, Thomas Gicquel, Pascal Guerard

Abstract readCase Reports
In one paragraph

Article in Archives of toxicology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Agathe PasquetLaboratoire de Pharmacologie et Toxicologie, Université Bourgogne Europe, CHU Dijon Bourgogne, Dijon, 21000, France. agathe.pasquet-ext@chu-dijon.fr.ORCID 0009-0004-2491-3047
Romain PelletierINSERM, Université de Rennes, INRAE, Institut NUMECAN (Nutrition, Métabolismes et Cancer) UMR_A, 1341, UMR_S 1317, Rennes, F-35000, France.
Roxane RouahService de Médecine légale, Université Bourgogne Europe, CHU Dijon Bourgogne, Dijon, 21000, France.
Tania PanterService de Médecine légale, Université Bourgogne Europe, CHU Dijon Bourgogne, Dijon, 21000, France.
Mélanie LoiseauService de Médecine légale, Université Bourgogne Europe, CHU Dijon Bourgogne, Dijon, 21000, France.
François-Hugues PoréeFaculté de Pharmacie, ISCR UMR CNRS 6226, Université de Rennes, 2 Avenue du Pr Léon Bernard, Rennes, 35000, France.
Thomas GicquelINSERM, Université de Rennes, INRAE, Institut NUMECAN (Nutrition, Métabolismes et Cancer) UMR_A, 1341, UMR_S 1317, Rennes, F-35000, France.
Pascal GuerardLaboratoire de Pharmacologie et Toxicologie, Université Bourgogne Europe, CHU Dijon Bourgogne, Dijon, 21000, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

N-ethylpentedrone (NEP) is a New Psychoactive Substance (NPS) of the cathinone class that has raised public health concerns, scheduled by both the United Nations Office on Drugs and Crime and the European Union Drugs Agency, since 2024. We report here a fatal case involving a 29-years-old man who used NEP in a chemsex context. Three plastic bags containing off-white to beige powders and crystals were found near the body. Proton and carbon nuclear magnetic resonance spectrometry (

Indexed as

HairPsychotropic DrugsSubstance Abuse DetectionAdultBiomarkersChemsexChromatography, High Pressure LiquidComputer SimulationFatal OutcomeHumansLiquid Chromatography-Mass SpectrometryMaleBiomarkersPsychotropic DrugsForensic toxicologyHair analysisHuman metabolismN-ethylpentedrone (NEP)New Psychoactive Substance (NPS)UHPLC-HRMS

Identifiers

PMID42228133
PMCPMC13593623

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.