Open-Irrigated Helical Radiofrequency Septal Ablation for Obstructive Hypertrophic Cardiomyopathy.

Yaxun Sun, Xiang Zhou, Mingdong Zhang, Guosheng Fu, Chenyang Jiang

Abstract readCase Reports

In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yaxun SunDepartment of Cardiology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China; Zhejiang Key Laboratory of Cardiovascular Intervention and Precision Medicine, Hangzhou, Zhejiang, China; Engineering Research Center for Cardiovascular Innovative Devices of Zhejiang Province, Hangzhou, Zhejiang, China. Electronic address: sunyaxun@zju.edu.cn.

Xiang ZhouDepartment of Cardiology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China; Zhejiang Key Laboratory of Cardiovascular Intervention and Precision Medicine, Hangzhou, Zhejiang, China; Engineering Research Center for Cardiovascular Innovative Devices of Zhejiang Province, Hangzhou, Zhejiang, China.

Mingdong ZhangSchool of Public Health, Fudan University, Shanghai, China; Suzhou SINUS MedTech, Suzhou, China.

Guosheng FuDepartment of Cardiology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China; Zhejiang Key Laboratory of Cardiovascular Intervention and Precision Medicine, Hangzhou, Zhejiang, China; Engineering Research Center for Cardiovascular Innovative Devices of Zhejiang Province, Hangzhou, Zhejiang, China.

Chenyang JiangDepartment of Cardiology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China; Zhejiang Key Laboratory of Cardiovascular Intervention and Precision Medicine, Hangzhou, Zhejiang, China; Engineering Research Center for Cardiovascular Innovative Devices of Zhejiang Province, Hangzhou, Zhejiang, China; Center for Cardiac Arrhythmias and Cardiomyopathy (Clinical & Research), Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeptal reduction therapy is recommended for symptomatic obstructive hypertrophic cardiomyopathy (oHCM) refractory to guideline-directed medical therapy. CASE SUMMARY: A 60-year-old man with drug-refractory oHCM underwent Percutaneous Helical Ablation of Septal hypErtrophy, using a novel, dedicated, open-irrigated helical radiofrequency catheter via subclavian venous access. The provoked left ventricular outflow tract gradient decreased immediately after ablation from 130 to 30 mm Hg, with sustained improvement at 12 months, septal fibrosis on 6-month cardiac magnetic resonance, symptomatic improvement, and no procedural or follow-up complications. DISCUSSION: This case report describes the first clinical use of a novel intervention strategy in oHCM. The hemodynamic benefit might be related to reduced septal contractility and a modest decrease in septal thickness. TAKE-HOME MESSAGE: This case demonstrates an ablation procedure using a dedicated open-irrigated helical radiofrequency catheter through subclavian venous access in oHCM.

Indexed as

ablationcardiomyopathyleft ventricle

Identifiers

PMID42227928

DOI10.1016/j.jaccas.2026.108475

PMCPMC13420660

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.