ArticleACS infectious diseases2026
Cytochrome P450-Mediated Metabolism of Antimycobacterial
Johannes Doering, Erik Meerz, Rüdiger W Seidel, Markus Lang, Andreas M Kany, Seppo Auriola, Risto Olavi Juvonen, Hannu Raunio, Richard Goddard, Matthew D Zimmerman and 4 more
Abstract read
In one paragraphArticle in ACS infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
14 authors.
Johannes DoeringInstitut für Pharmazie, Martin-Luther-Universität Halle-Wittenberg, Wolfgang-Langenbeck-Str. 4, 06120 Halle (Saale), Germany.
Erik MeerzInstitut für Pharmazie, Martin-Luther-Universität Halle-Wittenberg, Wolfgang-Langenbeck-Str. 4, 06120 Halle (Saale), Germany.
Rüdiger W SeidelInstitut für Pharmazie, Martin-Luther-Universität Halle-Wittenberg, Wolfgang-Langenbeck-Str. 4, 06120 Halle (Saale), Germany.ORCID 0000-0003-3438-4666 Markus LangInstitut für Pharmazie, Martin-Luther-Universität Halle-Wittenberg, Wolfgang-Langenbeck-Str. 4, 06120 Halle (Saale), Germany.
Andreas M KanyHelmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI), Campus Building E8.1, 66123 Saarbrücken, Germany.
Seppo AuriolaSchool of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Box 1627, Kuopio FI-70211, Finland.
Risto Olavi JuvonenSchool of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Box 1627, Kuopio FI-70211, Finland.ORCID 0000-0001-9240-7673 Hannu RaunioSchool of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Box 1627, Kuopio FI-70211, Finland.
Richard GoddardMax-Planck-Institut für Kohlenforschung, Kaiser-Wilhelm-Platz 1, 45470 Mülheim an der Ruhr, Germany.ORCID 0000-0003-0357-3173 Matthew D ZimmermanCenter for Discovery and Innovation, Hackensack Meridian Health, Nutley, New Jersey 07110,United States.
Véronique DartoisCenter for Discovery and Innovation, Hackensack Meridian Health, Nutley, New Jersey 07110,United States.ORCID 0000-0001-9470-5009 Anna K H HirschHelmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI), Campus Building E8.1, 66123 Saarbrücken, Germany.ORCID 0000-0001-8734-4663 Thomas DickCenter for Discovery and Innovation, Hackensack Meridian Health, Nutley, New Jersey 07110,United States.ORCID 0000-0002-9604-9452 Adrian RichterInstitut für Pharmazie, Martin-Luther-Universität Halle-Wittenberg, Wolfgang-Langenbeck-Str. 4, 06120 Halle (Saale), Germany.ORCID 0000-0002-0062-7896 Funding
Discovery of novel lead-target pairs and identification of all-oral bactericidal drug regimens for Mycobacterium abscessus lung diseaseR01AI132374 · NIAID · RBHS-NEW JERSEY MEDICAL SCHOOL · PI Thomas Dick · 2018 to 2026
$7.0MNIAID NIH HHS R01 AI132374
6 · The paper itselfAbstract
PubMed holds no abstract for this paper.
Indexed as
AmidesAnti-Bacterial AgentsCytochrome P-450 Enzyme SystemPhenylalanineAnimalsChromatography, LiquidMycobacterium tuberculosisOxidation-ReductionTandem Mass SpectrometryAmidesAnti-Bacterial AgentsCytochrome P-450 Enzyme SystemPhenylalanine
Identifiers
PMID42227659
PMCPMC13270519
What OpenQuestion holds
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LicenceCC BY
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