ArticleJournal of the Turkish German Gynecological Association2026
The association of pathological findings in HPV-31 positive women with high-grade squamous intraepithelial lesions.
Article in Journal of the Turkish German Gynecological Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To evaluate pathological findings in patients positive for human papillomavirus (HPV)-31. Material and Methods: This retrospective study included patients evaluated in a tertiary colposcopy clinic. The 3,546 patients tested for high-risk HPV were evaluated from September 2019 to December 2023. The study comprised 130 (3.7%) patients who tested positive for HPV-31. Isolated HPV-31 positivity indicated the presence of HPV-31 alone. Combined positivity indicated coexistence with other high-risk HPV types. If the following lesions were positive, high-grade squamous intraepithelial lesions (HSILs), adenocarcinoma Results: The mean age was 44.4±9.24 years. Isolated HPV-31 positivity was present in 69 (53.1%) patients. The final pathologic result was ≥HSIL in 9 (6.9%) patients, with only 1 (0.8%) patient had squamous cell cervical cancer. No significant association was observed between HPV-31 positivity type (isolated or combined) and ≥HSIL (respectively, 7.2% vs. 6.6%; p=0.578). Conclusion: Approximately 7% of women positive for HPV-31 have HSIL and higher lesions. The isolated or combined HPV-31 positivity does not affect the existence of HSIL or higher lesions.
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