Evidence map›Paper›PMID 42227372›Full record

ReviewEndocrine, metabolic & immune disorders drug targets2026

Global Research Trends in Innate Lymphoid Cells in the Gut and Kidney: A Bibliometric and Visual Analysis.

Xing Zhang, Gengxin Liu, Ziyou Yan

Abstract readReview
In one paragraph

Review in Endocrine, metabolic & immune disorders drug targets, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xing ZhangSchool of Traditional Chinese Medicine, Shandong University of Chinese Medicine, Jinan, China.
Gengxin LiuDepartment of Traditional Chinese Medicine, Jinan People's Hospital, Jinan, China.ORCID 0000-0003-1017-4808
Ziyou YanSchool of Clinical Medicine, Jiangxi University of Traditional Chinese Medicine, Nan Chang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionInnate lymphoid cells (ILCs), critical immune regulators in mucosal tissues, maintain tissue homeostasis, modulate inflammation, and drive immune defense. While their roles in gut and kidney biology are increasingly studied, global research trends and focal points in this field remain largely uncharacterized.

methodsUsing the Web of Science Core Collection (2004-2024), we analyzed 6,835 articles on gut- and kidney-associated ILCs. Bibliometric tools (VOSviewer, CiteSpace) were employed to evaluate publication trends, collaborations, institutional contributions, author influence, journal profiles, and keyword patterns to identify research priorities. Results and Discission: Annual publications surged from 2004 to 2024, peaking at 622 in 2024. The U.S. (2,145 articles), China (1,539), and Germany (679) dominated output, with Harvard Medical School and Inserm as leading institutions. Gregory F. Sonnenberg and David Artis were the most-cited authors. Key journals included

conclusionThis study underscores the therapeutic potential of ILCs in inflammation and cancer within the gut and kidney, advocating for interdisciplinary collaboration to advance mechanistic and clinical research.

Indexed as

BibliometricsBiomedical ResearchGastrointestinal TractImmunity, InnateKidneyLymphocytesAnimalsHumansgutimmunityinflammationinflammatory bowel diseaseInnate lymphoid cellskidney

Identifiers

PMID42227372
PMCPMC13662723

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.