Evidence map›Paper›PMID 42227288›Full record

ArticleSmall (Weinheim an der Bergstrasse, Germany)2026

Biomimetic TME-Responsive Nanotheranostics for Precise NIR-II Ratiometric Photoacoustic Imaging and Synergistic Immuno-Photothermal Therapy.

Xin Li, Hongrui Qiu, Lik Hang Hugo Tse, Xuehan Wang, Hsuan Lo, Huili Wang, Qi Li, Shiying Li, Yanjuan Gu, Wing-Tak Wong

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Small (Weinheim an der Bergstrasse, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xin LiDepartment of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, China.
Hongrui QiuGuangdong Provincial People's Hospital, Guangdong Academy of Medical Science, Southern Medical University, Guangzhou, China.
Lik Hang Hugo TseDepartment of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, China.
Xuehan WangDepartment of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, China.
Hsuan LoDepartment of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, China.
Huili WangGuangdong Provincial People's Hospital, Guangdong Academy of Medical Science, Southern Medical University, Guangzhou, China.
Qi LiGuangdong Provincial People's Hospital, Guangdong Academy of Medical Science, Southern Medical University, Guangzhou, China.
Shiying LiThe Hong Kong Polytechnic University Shenzhen Research Institute, Shenzhen, Guangdong, China.
Yanjuan GuDepartment of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, China.
Wing-Tak WongDepartment of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, China.ORCID https://orcid.org/0000-0002-3453-1825

Funding

Shenzhen Science and Technology Innovation Committee JCYJ20240813162028036
6 · The paper itself

Abstract

The complex immunosuppressive microenvironment of triple-negative breast cancer (TNBC) remains a major obstacle in attaining long-term clinical success and halting metastatic progression. To address this, the rational design of tumor microenvironment (TME)-responsive nanotheranostics is crucial for converting 'cold' tumors into 'hot' ones through synchronized imaging and precision therapy. Herein, we present a biomimetic, stimuli-activatable assembly (Au/Ag@HMON-NLG@CCM) utilizing a H

Indexed as

BiomimeticsImmunotherapyPhotoacoustic TechniquesPhotothermal TherapyTheranostic NanomedicineTumor MicroenvironmentAnimalsCell Line, TumorFemaleGoldHumansHydrogen PeroxideInfrared RaysMiceGoldHydrogen PeroxideIDO inhibitionnanotheranosticsphotoacoustic imagingsecond near‐infrared (NIR‐II) windowsynergistic immuno‐photothermal therapy

Identifiers

PMID42227288
PMCPMC13392700

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.