ReviewEFORT open reviews2026
Asymmetrical biomechanics in knee osteoarthritis: a review of contralateral risk from primary disease to post-arthroplasty progression.
Review in EFORT open reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Knee osteoarthritis (OA) demonstrates asymmetric joint degeneration (contrasting with symmetric inflammatory arthritis), driven by abnormal lower-limb biomechanics. Patients exhibit persistent inter-limb asymmetries in kinematics (reduced knee flexion/range of motion), kinetics (elevated knee adduction moment and increased contralateral loading), plantar pressure distribution, and muscle strength (15-30% quadriceps deficit), even with bilaterally matched disease severity. These asymmetries endure for months to years after total knee arthroplasty (TKA), manifesting as reduced weight-bearing on the operated limb and compensatory overloading of the contralateral limb. The high incidence of contralateral TKA (39% within 10 years) underscores the clinical importance of persistent biomechanical asymmetry as a prominent and modifiable contributor to OA progression in the opposite knee. Targeted rehabilitation strategies promoting inter-limb symmetry may mitigate disease advancement and improve functional outcomes.
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