Evidence map›Paper›PMID 42227043›Full record

ArticleOrganic letters2026

Asymmetric Deoxy-Fluoroalkylation of Amides Enabled by Transimination.

Jason A Wilt, Samirah Muhammad, R Yasoda H Rajapaksha, Erin K Batchelor, Danny Yang, Ethan Apsley, Jacob Moore, Byoungmoo Kim

Abstract read
In one paragraph

Article in Organic letters, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jason A WiltDepartment of Chemistry, Clemson University, Clemson, South Carolina 29634, United States.
Samirah MuhammadDepartment of Chemistry, Clemson University, Clemson, South Carolina 29634, United States.
R Yasoda H RajapakshaDepartment of Chemistry, Clemson University, Clemson, South Carolina 29634, United States.
Erin K BatchelorDepartment of Chemistry, Clemson University, Clemson, South Carolina 29634, United States.
Danny YangDepartment of Chemistry, Clemson University, Clemson, South Carolina 29634, United States.
Ethan ApsleyDepartment of Chemistry, Clemson University, Clemson, South Carolina 29634, United States.
Jacob MooreDepartment of Chemistry, Clemson University, Clemson, South Carolina 29634, United States.
Byoungmoo KimDepartment of Chemistry, Clemson University, Clemson, South Carolina 29634, United States.ORCID 0000-0002-1428-7896

Funding

Asymmetric Deoxygenative Diversification of Alcohols and Carboxylic AcidsR35GM160275 · NIGMS · CLEMSON UNIVERSITY · PI Byoungmoo Kim · 2025 to 2026
$706k
NIGMS NIH HHS R35 GM160275
6 · The paper itself

Abstract

Asymmetric deoxy-fluoroalkylation of amides remains a highly challenging goal, especially for accessing chiral α-fluoroalkyl amines, prevalent motifs in pharmaceuticals. Herein, we report a new sequential strategy for an asymmetric deoxy-fluoroalkylation of amides, enabling synthesis of diverse chiral α-fluoroalkyl amines bearing CF

Identifiers

PMID42227043
PMCPMC13404944

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.