Evidence map›Paper›PMID 42226874›Full record

ArticleCureus2026

Retrosternal Multinodular Goiter With Extensive Mediastinal Extension Requiring Combined Cervical Thyroidectomy and Median Sternotomy: A Case Report.

Jonathan A Charles, Stairis P Vinoj, Steles P Vinoj, Chirag Gaba, Akash Rahangan, Dheenu S

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jonathan A CharlesDepartment of Medicine and Surgery, SRM Medical College Hospital and Research Centre, Chengalpattu, IND.
Stairis P VinojDepartment of Medicine and Surgery, SRM Medical College Hospital and Research Centre, Chengalpattu, IND.
Steles P VinojDepartment of Medicine and Surgery, SRM Medical College Hospital and Research Centre, Chengalpattu, IND.
Chirag GabaDepartment of Medicine and Surgery, SRM Medical College Hospital and Research Centre, Chengalpattu, IND.
Akash RahanganDepartment of Pharmacology, SRM Medical College Hospital and Research Centre, Chengalpattu, IND.
Dheenu SDepartment of General Surgery, SRM Medical College Hospital and Research Centre, Chengalpattu, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retrosternal goiter is a distinct clinical entity, characterized by extension of thyroid tissue into the mediastinum, often increasing surgical complexity and necessitating individualized operative planning. We report a 55-year-old female patient presenting with a gradually enlarging anterior neck swelling without compressive or thyrotoxic symptoms. Clinical examination suggested mediastinal extension, and imaging with contrast-enhanced computed tomography confirmed a large multinodular goiter extending retrosternally up to the level of the D7 vertebra, abutting major mediastinal vessels without encasement. Fine-needle aspiration cytology was benign (Bethesda Category II). In view of the significant intrathoracic extension and proximity to vital structures, the patient underwent total thyroidectomy with a combined cervical approach and median sternotomy. Histopathological examination confirmed multinodular goiter without evidence of malignancy. The postoperative course was uneventful, and the patient remained asymptomatic on follow-up. This case highlights the importance of preoperative imaging in defining mediastinal extent and guiding surgical approach, emphasizing that extensive retrosternal extension and vascular proximity may necessitate a combined cervicothoracic approach to ensure safe and complete excision with minimal complications.

Indexed as

case reportsmediastinummultinodular goiterretrosternal goitersternotomysubsternal goiterthyroidectomythyroid glandthyroid goiterthyroid neoplasms

Identifiers

PMID42226874
PMCPMC13222671

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