Evidence map›Paper›PMID 42226873›Full record

ArticleCureus2026

Adult Langerhans Cell Histiocytosis Presenting as an Isolated Rectal Polyp and Hematochezia.

Liena Zhao, David Driman

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Liena ZhaoDepartment of Pathology and Laboratory Medicine, London Health Sciences Centre, Western University, London, CAN.
David DrimanDepartment of Pathology and Laboratory Medicine, London Health Sciences Centre, Western University, London, CAN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Langerhans cell histiocytosis (LCH) is a rare disorder characterized by the abnormal proliferation and accumulation of Langerhans cells, which are specialized dendritic cells involved in antigen presentation. LCH most commonly involves the skin, bone, and lung. The gastrointestinal tract is an uncommon site of disease, and LCH presenting as a solitary colonic polyp is extremely rare. We present a case of a 53-year-old male with hematochezia who had a rectal polyp that was confirmed both histologically and immunohistochemically to be LCH. There was no evidence of systemic involvement of LCH.

Indexed as

colorectalgastrointestinalhematochezialangerhans cell histiocytosis(lch)polyp

Identifiers

PMID42226873
PMCPMC13222503

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.