Evidence map›Paper›PMID 42226812›Full record

ArticleAlzheimer's & dementia. Behavior & socioeconomics of aging2026

Alcohol use and

Edna P Mendoza-Villena, Malinee Neelamegam, Nicole Phillips, Leigh Johnson, Lubnaa Abdullah, James Hall, Sid O'Bryant, Eun-Young Mun, Shea J Andrews, Robert Barber and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Alzheimer's & dementia. Behavior & socioeconomics of aging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Edna P Mendoza-VillenaDepartment of Population and Community Health, University of North Texas Health Fort Worth, Fort Worth, Texas, USA.
Malinee NeelamegamDepartment of Population and Community Health, University of North Texas Health Fort Worth, Fort Worth, Texas, USA.
Nicole PhillipsDepartment of Microbiology, Immunology, and Genetics, University of North Texas Health Fort Worth, Fort Worth, Texas, USA.
Leigh JohnsonInstitute for Translational Research, University of North Texas Fort Worth, Fort Worth, Texas, USA.
Lubnaa AbdullahInstitute for Translational Research, University of North Texas Fort Worth, Fort Worth, Texas, USA.
James HallInstitute for Translational Research, University of North Texas Fort Worth, Fort Worth, Texas, USA.
Sid O'BryantInstitute for Translational Research, University of North Texas Fort Worth, Fort Worth, Texas, USA.
Eun-Young MunDepartment of Population and Community Health, University of North Texas Health Fort Worth, Fort Worth, Texas, USA.
Shea J AndrewsDepartment of Psychiatry and Behavioral Sciences, University of California San Francisco, San Francisco, California, USA.
Robert BarberInstitute for Translational Research, University of North Texas Fort Worth, Fort Worth, Texas, USA.
Gita A PathakThe Institute for Genomic Health, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Mohammad HousiniDepartment of Family Medicine and Osteopathic Manipulative Medicine, University of North Texas Fort Worth, Fort Worth, Texas, USA.
Kai ZhangDepartment of Population and Community Health, University of North Texas Health Fort Worth, Fort Worth, Texas, USA.
Zhengyang ZhouDepartment of Population and Community Health, University of North Texas Health Fort Worth, Fort Worth, Texas, USA.ORCID 0000-0002-8039-418X

Funding

Project 1U19AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI Laurel A Beckett · 2016 to 2026
$226.7M
The Health & Aging Brain Study - Health Disparities (HABS-HD)U19AG078109 · NIA · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI LEIGH A JOHNSON · 2022 to 2026
$181.1M
Health and Aging Brain among Latino Elders (HABLE-AT(N)) StudyR01AG058533 · NIA · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI JOHNSON, LEIGH A, O'BRYANT, SID E · 2020 to 2025
$45.4M
Health Disparities in Alzheimer's Disease and Mild Cognitive Impairment among Mexican AmericansR01AG054073 · NIA · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI O'BRYANT, SID E, TOGA, ARTHUR W · 2017 to 2021
$12.6M
Epigenetic Risk Factors for AD Age at Onset and Health Disparities: HABLE Epigenetics StudyR01AG070862 · NIA · UNIVERSITY OF NORTH TEXAS HLTH SCI CTR · PI BARBER, ROBERT CLINTON · 2021 to 2025
$3.4M
Genome-wide screen for dynamic gene-environment interactionsR03ES034138 · NIEHS · UT SOUTHWESTERN MEDICAL CENTER · PI XING, CHAO · 2022 to 2023
$174k
NIA NIH HHS R01 AG054073NIA NIH HHS R01 AG058533NIA NIH HHS R01 AG070862NIA NIH HHS U19 AG024904NIA NIH HHS U19 AG078109NIEHS NIH HHS R03 ES034138
6 · The paper itself

Abstract

Introduction: We investigated the interaction between alcohol use behavior and apolipoprotein E ( Methods: Using the Health and Aging Brain Study-Health Disparities data, we analyzed 2143 adults aged 50+ using linear regression analysis with interaction between alcohol use and Results: Cognitive performance was negatively associated with alcohol use among Discussion:

Indexed as

alcoholapolipoprotein E ε4cognitive domainsdose–responseHealth and Aging Brain Study–Health Disparitiesinteraction

Identifiers

PMID42226812
PMCPMC13220920

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.