Evidence map›Paper›PMID 42226800›Full record

ArticleSensors and actuators. B, Chemical2026

Noninvasive Monitoring of Skin pH Changes Induced by Microneedle Electroporation.

Dengning Xia, Huan Yu, Song Li, Mark R Prausnitz

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Sensors and actuators. B, Chemical, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dengning XiaSchool of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen 518107, China.
Huan YuSchool of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA 30332 USA.
Song LiSchool of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA 30332 USA.
Mark R PrausnitzSchool of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA 30332 USA.

Funding

Multivalent nanocluster universal influenza vaccine given by microneedle patchR01AI143844 · NIAID · GEORGIA STATE UNIVERSITY · PI WANG, BAOZHONG · 2019 to 2023
$3.9M
NIAID NIH HHS R01 AI143844
6 · The paper itself

Abstract

The pH of the skin surface plays a critical role in maintaining epidermal homeostasis and barrier function. Microneedle electroporation represents a pivotal advancement in transdermal drug and gene delivery; however, the concomitant electrochemical reactions that pose risks of cutaneous pH perturbation have not been experimentally characterized. This study establishes a quantitative, noninvasive analytical methodology to visualize and measure these microenvironmental changes

Indexed as

electroporationMicroneedleRatiometric fluorescence imagingSkin pH microenvironment

Identifiers

PMID42226800
PMCPMC13218681

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.