Evidence map›Paper›PMID 42226502›Full record

ReviewElectrophoresis2026

Cyclodextrins as Chiral Selectors in Capillary Electrophoresis-Recent Developments in Understanding Analyte Complexation and Applications in Pharmaceutical Analysis.

Gerhard K E Scriba

Abstract readReview
In one paragraph

Review in Electrophoresis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Gerhard K E ScribaDepartment of Pharmaceutical/Medicinal Chemistry, Friedrich Schiller University Jena, Jena, Germany.ORCID https://orcid.org/0000-0003-2950-060X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CDs, cyclic oligosaccharides consisting of α-1,4 linked d-glucopyranose units, have been applied in many areas, such as food, cosmetics, environmental, agriculture, textile, pharmaceutical, and chemical industries, due to their ability to form guest-host complexes. Because CDs are chiral compounds, they have also been successfully used as chiral selectors in analytical enantioseparation techniques, especially CE. In the last decades, multidisciplinary approaches have been performed, combining CE with NMR spectroscopy, molecular modeling, and other techniques in order to understand aspects of chiral recognition underlying enantioseparations. The present review focuses on such mechanistic studies published between January 2023 and March 2026 in addition to the application of CD-mediated CE enantioseparations to the determination of the enantiomeric purity of drug substances as well as the analysis of pharmaceutical formulations.

Indexed as

CyclodextrinsElectrophoresis, CapillaryPharmaceutical PreparationsStereoisomerismCyclodextrinsPharmaceutical Preparationschiral recognition mechanismcyclodextrinenantiomeric purityenantioseparationpharmaceutical analysis

Identifiers

PMID42226502
PMCPMC13480575

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.