Evidence map›Paper›PMID 42226348›Full record

ArticleJournal of experimental zoology. Part A, Ecological and integrative physiology2026

Prolactin and Triiodothyronine Modulate Seasonal Variation in Brown Adipose Tissue in Djungarian Hamsters.

Sayantan Sur, Grace Payling, Calum Stewart, Avalene Tan, Caitlin Diggle, Tyler J Stevenson

Abstract read
In one paragraph

Article in Journal of experimental zoology. Part A, Ecological and integrative physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Prolactin and Triiodothyronine Modulate Seasonal Variation in Brown Adipose Tissue in Djungarian Hamsters.Journal of experimental zoology. Part A, Ecological and integrative physiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sayantan SurSchool of Biodiversity, One Health & Veterinary Medicine, University of Glasgow, Glasgow, UK.ORCID https://orcid.org/0000-0002-4273-0488
Grace PaylingSchool of Biodiversity, One Health & Veterinary Medicine, University of Glasgow, Glasgow, UK.
Calum StewartSchool of Biodiversity, One Health & Veterinary Medicine, University of Glasgow, Glasgow, UK.
Avalene TanThe University of Texas at Dallas (UT Dallas), Dallas, Texas, USA.
Caitlin DiggleSchool of Biodiversity, One Health & Veterinary Medicine, University of Glasgow, Glasgow, UK.
Tyler J StevensonSchool of Biodiversity, One Health & Veterinary Medicine, University of Glasgow, Glasgow, UK.

Funding

Leverhulme Trust RL-2019-006
6 · The paper itself

Abstract

Seasonal photoperiodic cycles regulate energy rheostasis in many animals. Brown adipose tissue (BAT) and the liver are key metabolic organs that show remarkable plasticity in response to photoperiodic conditions. Prolactin (PRL) and thyroid hormones are endocrine signals that transmit neural-derived photoperiodic time measurement encoding to regulate peripheral tissues. Using Djungarian hamsters (Phodopus sungorus), a well-established seasonal model, we examined the effects of photoperiod, triiodothyronine (T3), and PRL on liver and brown adipose tissue morphology and lipid content. Tissue mass, brown adipose tissue somatic index, and histological lipid content were quantified in three experiments that investigated tissue variation (1) across photoinduced seasonal cycles, and the sufficiency of acute (2) triiodothyronine, and (3) prolactin administration. Long photoperiod (LP) exposure maintained large BAT and higher lipid content, whereas short photoperiod (SP) exposure reduced BAT mass and lipid content. T3 treatment increased the BAT mass but did not impact lipid content. Conversely, PRL treatment increased BAT lipid content but did not impact tissue mass. Together, these findings identify triiodothyronine and prolactin as critical regulators of metabolic tissues.

Indexed as

Adipose Tissue, BrownPhodopusProlactinSeasonsTriiodothyronineAnimalsCricetinaeLipid MetabolismLiverMalePhotoperiodProlactinTriiodothyronineadiposelivermammalsmetabolismphotoperiodrheostasis

Identifiers

PMID42226348
PMCPMC13353641

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.