Evidence map›Paper›PMID 42226342›Full record

ArticlePest management science2026

Design, synthesis, and antiviral activity of novel piperidine-containing pyrazoleamide derivatives.

Wei Sun, Anjing Liao, Ya Wang, Xinyi Zhang, Han Yan, Fangxing Wang, Shengxin Guo, Jian Wu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pest management science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wei SunState Key Laboratory of Green Pesticide, Center for Research and Development of Fine Chemicals, Guizhou University, Guiyang, China.
Anjing LiaoState Key Laboratory of Green Pesticide, Center for Research and Development of Fine Chemicals, Guizhou University, Guiyang, China.
Ya WangState Key Laboratory of Green Pesticide, Center for Research and Development of Fine Chemicals, Guizhou University, Guiyang, China.
Xinyi ZhangState Key Laboratory of Green Pesticide, Center for Research and Development of Fine Chemicals, Guizhou University, Guiyang, China.
Han YanState Key Laboratory of Green Pesticide, Center for Research and Development of Fine Chemicals, Guizhou University, Guiyang, China.
Fangxing WangState Key Laboratory of Green Pesticide, Center for Research and Development of Fine Chemicals, Guizhou University, Guiyang, China.
Shengxin GuoState Key Laboratory of Green Pesticide, Center for Research and Development of Fine Chemicals, Guizhou University, Guiyang, China.
Jian WuState Key Laboratory of Green Pesticide, Center for Research and Development of Fine Chemicals, Guizhou University, Guiyang, China.ORCID https://orcid.org/0000-0002-0740-0280

Funding

Science and Technology Plan Project of Guizhou ProvinceThe financial support from the National Natural Science Foundation of China 32472623the Program of Introducing Talents to Chinese Universities D20023
6 · The paper itself

Abstract

backgroundPlant viruses such as tobacco mosaic virus (TMV) pose a serious threat to global crop production, making the development of highly effective antiviral agents an urgent task in agricultural plant protection.

resultsThree series of pyrazoleamide-piperidine derivatives were designed and synthesized, and their antiviral activities against TMV were evaluated. Compounds H9 and X18 exhibited protective half-maximal effective concentration (EC

conclusionCompounds H9 and X18 enhanced TMV resistance through distinct mechanisms, informing the development of novel green antiviral agents. © 2026 Society of Chemical Industry.

Indexed as

AmidesAntiviral AgentsPiperidinesPlant DiseasesPyrazolesTobacco Mosaic VirusDrug DesignAmidesAntiviral AgentspiperidinePiperidinesPyrazolesantiviral activitymechanism of actionpiperidinepyrazoleamide

Identifiers

PMID42226342
PMCPMC13453190

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.