Evidence map›Paper›PMID 42226206›Full record

ArticleBiology of sex differences2026

Sex differences in activations to the sight of faces, scenes, body parts and tools in visual and non-visual cortical regions leading to the human hippocampus.

Ruohan Zhang, Edmund T Rolls, Jianfeng Feng

Abstract read
In one paragraph

Article in Biology of sex differences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

3 authors.

Ruohan Zhang *Warwick Manufacturing Group, University of Warwick, Coventry, CV4 7AL, UK. Ruohan.Zhang.2@warwick.ac.uk.
Edmund T Rolls *Department of Computer Science, University of Warwick, Coventry, CV4 7AL, UK. Edmund.Rolls@oxcns.org.ORCID 0000-0003-3025-1292
Jianfeng FengDepartment of Computer Science, University of Warwick, Coventry, CV4 7AL, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In a large Human Connectome Project dataset of 504 females and 452 males performing a 0-back memory task with visual images using the HCP-MultiModalParcellation, faces activated some key cortical regions more (using FDR correction) in females than males, including in the left hemisphere the fusiform face cortex and inferior temporal visual cortex TE2p; and visual motion regions in the MT+ complex. The sight of scenes activated more in males than females scene-related cortical regions including the medial parahippocampal scene (or place) regions such as PHA2 and earlier regions in the ventromedial cortical visual scene stream such as POS2, with differences found in both hemispheres. The sight of body parts activated more in females than males the inferior temporal visual cortex TE2p, some MT+ visual motion regions such as FST and PH, and also the perirhinal 'What' visual stream input to the hippocampal system via the perirhinal cortex, PeEc, in the left hemisphere. The sight of tools activated more in males than females and in the left hemisphere anterior temporal lobe regions such as TE2a, and regions that provide 'What' inputs to the hippocampal system, the lateral parahippocampal cortex and perirhinal cortex, PeEc. These cortical specialisations are likely to be relevant to behavioral differences for females compared to males in the processing of socially relevant stimuli such as faces and body parts; and to behavioral differences for males compared to females in the processing of spatial scenes and tools, with behavioral sex differences for scenes vs. faces present in these participants.

Indexed as

HippocampusSex CharacteristicsVisual CortexVisual PerceptionAdultFemaleHuman BodyHumansMagnetic Resonance ImagingMaleYoung AdultActivations to faces, places, body parts, and toolsCortical scene regionsHuman connectomeHuman visual cortexSex differencesVentromedial visual cortical stream

Identifiers

PMID42226206
PMCPMC13292326

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.