Evidence map›Paper›PMID 42226176›Full record

ArticleBMC public health2026

The association between adult height and the incidence of diabetes in a Japanese working population: a prospective study exploring the possible role of cohort effects.

Rachana Manandhar Shrestha, Huan Hu, Yosuke Inoue, Shohei Yamamoto, Ami Fukunaga, Takeshi Kochi, Naoki Gommori, Toshiaki Miyamoto, Makoto Yamamoto, Hiroko Okazaki and 9 more

Abstract read
In one paragraph

Article in BMC public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Rachana Manandhar ShresthaDepartment of Epidemiology and Prevention, Center for Clinical Sciences, Japan Institute for Health Security, 1-21-1 Toyama, Shinjuku-ku, 162-8655, Tokyo, Japan.ORCID http://orcid.org/0000-0001-9289-8070
Huan HuDepartment of Epidemiology and Prevention, Center for Clinical Sciences, Japan Institute for Health Security, 1-21-1 Toyama, Shinjuku-ku, 162-8655, Tokyo, Japan.ORCID http://orcid.org/0000-0001-8558-2895
Yosuke InoueDepartment of Epidemiology and Prevention, Center for Clinical Sciences, Japan Institute for Health Security, 1-21-1 Toyama, Shinjuku-ku, 162-8655, Tokyo, Japan. yosuke.yoshi.yosky@gmail.com.ORCID http://orcid.org/0000-0002-7690-3447
Shohei YamamotoDepartment of Epidemiology and Prevention, Center for Clinical Sciences, Japan Institute for Health Security, 1-21-1 Toyama, Shinjuku-ku, 162-8655, Tokyo, Japan.ORCID http://orcid.org/0000-0001-6503-8577
Ami FukunagaDepartment of Epidemiology and Prevention, Center for Clinical Sciences, Japan Institute for Health Security, 1-21-1 Toyama, Shinjuku-ku, 162-8655, Tokyo, Japan.ORCID http://orcid.org/0000-0002-8705-0056
Takeshi KochiFurukawa Electric Co., Ltd., Tokyo, 100-8322, Japan.
Naoki GommoriEast Japan Works (Keihin), JFE Steel Corporation, Kanagawa, 210-0866, Japan.
Toshiaki MiyamotoEAST NIPPON WORKS Kimitsu Area, NIPPON STEEL CORPORATION, Chiba, 299-1141, Japan.
Makoto YamamotoYAMAHA CORPORATION, Shizuoka, 430-8650, Japan.
Hiroko OkazakiMitsui Chemicals, Inc., Tokyo, 104-0028, Japan.
Hiroshi IdeMitsui Chemicals, Inc., Tokyo, 104-0028, Japan.
Tohru NakagawaHitachi Health Care Center, Hitachi, Ltd., Ibaraki, 317-0076, Japan.
Toru HondaHitachi Health Care Center, Hitachi, Ltd., Ibaraki, 317-0076, Japan.
Shuichiro YamamotoHitachi Health Care Center, Hitachi, Ltd., Ibaraki, 317-0076, Japan.
Kenya YamamotoDivision of Chemical Information, National Institute of Occupational Safety and Health, Kanagawa, 214-8585, Japan.
Maki KonishiDepartment of Epidemiology and Prevention, Center for Clinical Sciences, Japan Institute for Health Security, 1-21-1 Toyama, Shinjuku-ku, 162-8655, Tokyo, Japan.ORCID http://orcid.org/0009-0009-6118-4513
Isamu KabeKUBOTA Corporation, Ibaraki, 300-2402, Japan.
Seitaro DohiMitsui Chemicals, Inc., Tokyo, 104-0028, Japan.
Tetsuya MizoueDepartment of Epidemiology and Prevention, Center for Clinical Sciences, Japan Institute for Health Security, 1-21-1 Toyama, Shinjuku-ku, 162-8655, Tokyo, Japan.ORCID http://orcid.org/0000-0002-1198-2228

Funding

Industrial Disease Clinical Research Grants 140202-01, 150903-01, and 170301-01Japan Institute for Health Security Intramural Research Fund 25A1005Japan Society for the Promotion of Science, Japan JP25293146, JP25702006, JP16H05251, JP20H03952National Center for Global Health and Medicine Intramural Research Fund 21A1020National Center for Global Health and Medicine Intramural Research Fund 28-Shi-1206, 30-Shi-2003, 19A1006, 22A1008
6 · The paper itself

Abstract

backgroundAdult height may reflect early-life environmental conditions that influence the risk of type 2 diabetes mellitus (DM). While taller height has been linked to lower DM risk, evidence from East Asia remains limited and inconsistent. Given that DM in East Asians often occurs at lower BMI levels, population-specific research is needed. We examined the prospective association between adult height and incident DM in a large Japanese working population, focusing on differences by sex and birth cohort.

methodsData were obtained from annual health checkups of 63,264 workers from 12 companies in Japan, comprising 54,188 men and 9076 women aged 20-64 years at baseline. Participants were classified by quartile of adult height for each sex. DM was defined as either when the participants had glycated hemoglobin (HbA1c) ≥ 6.5%, random glucose ≥ 200 mg/dL, fasting glucose ≥ 126 mg/dL, or when they were receiving antidiabetic treatment. Time ratios (TRs) and 95% confidence intervals (CIs) for the duration of remaining free from DM were estimated using a sex-stratified accelerated failure time model. We also examined whether the association varied by birth cohort, by comparing individuals born in 1960 or earlier with those born later.

resultsDuring a median follow-up period of 9.4 years, 5829 men and 448 women developed DM. For the highest vs. lowest height categories, after adjusting for age, body mass index, smoking, hypertension, and dyslipidemia, the TRs were 1.07 (95% CI, 1.02-1.13) in men and 0.98 (95% CI: 0.91-1.06) in women, respectively. When we stratified by birth cohorts, the height-DM association among men was more pronounced in the older cohort compared to the younger cohort.

conclusionsIn a large cohort of Japanese workers, taller stature was associated with a prolonged duration of DM-free survival among men, particularly those in older cohorts. In women, however, the association between height and diabetes risk was inconclusive and warrants further investigation. The impact of stature on the risk of DM may be affected by sex and cohort effects, necessitating further research to disentangle these effects.

Indexed as

Body HeightDiabetes Mellitus, Type 2AdultBirth CohortEast Asian PeopleFemaleHumansIncidenceJapanMaleMiddle AgedProspective StudiesRisk FactorsYoung AdultAdult heightDiabetesJapanProspective study

Identifiers

PMID42226176
PMCPMC13435464

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.