Evidence map›Paper›PMID 42226130›Full record

ArticleBMC medical research methodology2026

A comparative simulation study of cluster ensemble algorithms integrated with multiple imputation for clustering with missing data.

Yui Tomo, Funato Sato, Mari Oba

Abstract readComparative Study
In one paragraph

Article in BMC medical research methodology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yui TomoDepartment of Epidemiology, National Institute of Infectious Diseases, Japan Institute for Health Security, Shinjuku-Ku, 162-0052, Tokyo, Japan. tomo.y@jihs.go.jp.
Funato SatoDepartment of Clinical Data Science, National Center of Neurology and Psychiatry, Kodaira, 187-8551, Tokyo, Japan.
Mari ObaDepartment of Clinical Data Science, National Center of Neurology and Psychiatry, Kodaira, 187-8551, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since cluster analysis methods usually cannot be applied directly to data with missing values, various approaches have been investigated to handle the problem. Multiple imputation is one of the standard procedures for addressing the problem of missing data. In cluster analysis, instead of Rubin's rule, cluster ensemble methods have been proposed to be combined with multiple imputation. However, it remains unrevealed which of the cluster ensemble algorithms leads to better performance when integrated with the procedure. Therefore, we conducted numerical comparisons of several algorithms to integrate the results from k-means++ clustering for multiply imputed datasets and also applied the combined approaches to two real datasets. Our results suggest that the non-negative matrix factorization algorithm may be suitable for scenarios with class balance, whereas the greedy and agglomerative cluster algorithms may be suitable for scenarios with class imbalance. Before application to actual datasets, we still recommend performing simulation experiments in scenarios reflecting the characteristics of the datasets and the assumption of missing value mechanisms.

Indexed as

AlgorithmsCluster AnalysisClustering AlgorithmsComputer SimulationData Interpretation, StatisticalEnsemble LearningHumansCluster analysisConsensus clusteringHierarchical clusteringK-meansNon-negative matrix factorization

Identifiers

PMID42226130
PMCPMC13439842

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.