Evidence map›Paper›PMID 42226107›Full record

ArticleBMC plant biology2026

Integrated physiological, element content, transcriptomic and weighted gene co-expression network analysis provide insights into the response mechanisms of Areca catechu to Zn/Fe deficiency stress.

Jing Yang, Weiying Li, Shangjia Du, Qiyuan An, Chuang Cui, Mengying Ding, Yicheng Wang, Guangzhen Zhou

Abstract read
In one paragraph

Article in BMC plant biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jing Yang *Ministry of Education Key Laboratory for Ecology of Tropical Islands, Key Laboratory of Tropical Animal and Plant Ecology of Hainan Province, College of Life Sciences, Hainan Normal University, Haikou, 571158, China.
Weiying Li *Ministry of Education Key Laboratory for Ecology of Tropical Islands, Key Laboratory of Tropical Animal and Plant Ecology of Hainan Province, College of Life Sciences, Hainan Normal University, Haikou, 571158, China.
Shangjia Du *Hainan Academy of Forestry (Hainan Academy of Mangrove), Haikou, 571100, China.
Qiyuan AnLiaoning Research Institute of Cash Crops, Liaoyang, 111000, China.
Chuang CuiSchool of Breeding and Multiplication (Sanya Institute of Breeding and Multiplication), School of Tropical Agriculture and Forestry (School of Agriculture and Rural Affairs & School of Rural Revitalization), Hainan University, Sanya, 572024, China.
Mengying DingMinistry of Education Key Laboratory for Ecology of Tropical Islands, Key Laboratory of Tropical Animal and Plant Ecology of Hainan Province, College of Life Sciences, Hainan Normal University, Haikou, 571158, China.
Yicheng WangSchool of Breeding and Multiplication (Sanya Institute of Breeding and Multiplication), School of Tropical Agriculture and Forestry (School of Agriculture and Rural Affairs & School of Rural Revitalization), Hainan University, Sanya, 572024, China.
Guangzhen ZhouMinistry of Education Key Laboratory for Ecology of Tropical Islands, Key Laboratory of Tropical Animal and Plant Ecology of Hainan Province, College of Life Sciences, Hainan Normal University, Haikou, 571158, China. gzzhou@hainanu.edu.cn.

Funding

the Hainan Normal University Talent Research Start-up Fund Project Funding HSZK-KYQD-202421
6 · The paper itself

Abstract

Zinc (Zn) and iron (Fe) deficiencies are pervasive abiotic stresses that severely limit the productivity and nutritional quality of tropical crops, including the economically important Areca catechu. To elucidate the comprehensive response mechanisms of areca to Zn/Fe deficiencies, we conducted an integrated multi-omics analysis. This combined physiological assessment, elemental profiling, transcriptomic sequencing, and weighted gene co-expression network analysis (WGCNA) on seedlings subjected to prolonged (45 day) Zn/Fe deficiency. Our results showed that this prolonged stress significantly altered leaf microstructure, reduced photosynthetic carbon (C) assimilation, and triggered tissue-specific compensatory accumulation of Fe (in L3 leaves under Zn deficiency) or Zn (in L3 leaves under Fe deficiency). Transcriptome sequencing revealed that phenylpropanoid/flavonoid biosynthesis and xyloglucan metabolism pathways were consistently enriched among differentially expressed genes (DEGs) across tissues. Seven stress-specific modules and hub genes related to Zn/Fe deficiency in areca were identified by WGCNA. These results demonstrated that phenylpropanoid/flavonoids metabolism and xyloglucan-mediated cell wall remodeling are central to Zn/Fe deficiency adaptation, while identified transporters and transcription factors (TFs) form critical regulatory networks in Zn/Fe homeostasis in A. catechu. Our study demonstrated the core adaptive pathways (phenylpropanoid/flavonoid and xyloglucan metabolism) and regulatory networks for areca's adaptation to Zn/Fe deficiency, providing genetic resources for breeding nutrient-efficient areca varieties.

Indexed as

ArecaIron DeficienciesTranscriptomeZincGene Expression ProfilingGene Expression Regulation, PlantGene Regulatory NetworksIronPlant LeavesStress, PhysiologicalIronZincAreca catechuMetal transportersWGCNAZn/Fe deficiency

Identifiers

PMID42226107
PMCPMC13439856

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.