Evidence map›Paper›PMID 42226098›Full record

ArticleBMC plant biology2026

Ectopic overexpression of cucumber CsBT2 gene increases drought and salt stress sensitivity in Arabidopsis.

Weifeng Huang, Zuying Zhou, Xueping Guo, Meng Wang, Jiajun Ye, Zhehan Wu, Feng Yang, Yong Zhou

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In one paragraph

Article in BMC plant biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Weifeng Huang *Guangdong Provincial Key Laboratory of Utilization and Conservation of Food and Medicinal Resources in Northern Region, School of Biology and Agriculture, Shaoguan University, Shaoguan, 512000, China.
Zuying Zhou *Key Laboratory of Crop Physiology, Ecology and Genetic Breeding, Ministry of Education, College of Bioscience and Bioengineering, Jiangxi Agricultural University, Nanchang, 330045, China.
Xueping Guo *Key Laboratory of Crop Physiology, Ecology and Genetic Breeding, Ministry of Education, College of Bioscience and Bioengineering, Jiangxi Agricultural University, Nanchang, 330045, China.
Meng WangKey Laboratory of Crop Physiology, Ecology and Genetic Breeding, Ministry of Education, College of Bioscience and Bioengineering, Jiangxi Agricultural University, Nanchang, 330045, China.
Jiajun YeKey Laboratory of Crop Physiology, Ecology and Genetic Breeding, Ministry of Education, College of Bioscience and Bioengineering, Jiangxi Agricultural University, Nanchang, 330045, China.
Zhehan WuKey Laboratory of Crop Physiology, Ecology and Genetic Breeding, Ministry of Education, College of Bioscience and Bioengineering, Jiangxi Agricultural University, Nanchang, 330045, China.
Feng YangKey Laboratory of Crop Physiology, Ecology and Genetic Breeding, Ministry of Education, College of Bioscience and Bioengineering, Jiangxi Agricultural University, Nanchang, 330045, China.
Yong ZhouKey Laboratory of Crop Physiology, Ecology and Genetic Breeding, Ministry of Education, College of Bioscience and Bioengineering, Jiangxi Agricultural University, Nanchang, 330045, China. yongzhou@jxau.edu.cn.

Funding

Doctoral Scientific Research Startup Foundation of Shaoguan University 9900064505the Key Projects of Shaoguan University SZ2023KJ04the Open Fund of the Guangdong Provincial Key Laboratory of Utilization and Conservation of Food and Medicinal Resources in Northern Region FMR2023002M
6 · The paper itself

Abstract

backgroundPlant-specific BTB-TAZ domain (BT) proteins play key roles in stress responses, while their functions in cucumber remain largely unclear.

resultsIn this study, we investigated the role of the CsBT2 gene under abiotic stress conditions. Tissue-specific expression analysis showed that CsBT2 is predominantly expressed in roots. qRT-PCR results indicated that its expression is regulated by salt stress, drought, and exogenous abscisic acid (ABA). To further explore its function, we generated CsBT2-overexpressing Arabidopsis transgenic plants and found that they exhibited enhanced sensitivity to salt and drought stress, manifested as reduced seed germination rates and inhibited root growth, with lower SOD activity and increased electrolyte leakage and MDA content. qRT-PCR analysis revealed that several stress-related genes, including AtRbohF, AtRD22, and AtRD29A, were downregulated in transgenic plants compared to wild-type (WT) plants under normal conditions. Additionally, the overexpression plants showed resistance to exogenous ABA-mediated root growth inhibition.

conclusionsCsBT2 acts as a negative regulator in cucumber responses to abiotic stress, likely by antagonizing ABA signaling and suppressing the expression of stress-related genes, thereby appears to negatively influence stress tolerance.

Indexed as

ArabidopsisCucumis sativusPlant ProteinsSalt StressAbscisic AcidDrought ResistanceDroughtsEctopic Gene ExpressionGene Expression Regulation, PlantGenes, PlantPlants, Genetically ModifiedStress, PhysiologicalAbscisic AcidPlant ProteinsBTB-TAZ (BT)CucumberDrought stressSalt stressTransgenic Arabidopsis

Identifiers

PMID42226098
PMCPMC13439882

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.