Evidence map›Paper›PMID 42226090›Full record

SynthesisJournal of neurologic physical therapy : JNPT2026

Efficacy of Physical Modalities for Hemiplegic Shoulder Pain After Stroke: A Systematic Review.

Stefania Spina, Salvatore Facciorusso, Milena Carmela D'Ascanio, Mirko Filippetti, Marco Battaglia, Alessio Baricich, Alessandro Picelli, Andrea Santamato

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of neurologic physical therapy : JNPT, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Stefania SpinaDepartment of Physical Medicine and Rehabilitation, Azienda Ospedaliero-Universitaria Ospedali Riuniti Di Foggia, Foggia, Italy (S.S., S.F., A.S.); Department of Medical and Surgical Science, University of Foggia, Foggia, Italy (S.S.); Unità di Riabilitazione, Presidio Ospedaliero San Camillo de Lellis ASL Foggia, Manfredonia, Italy (M.C.D'A.); Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy (M.F., A.P.); Rehabilitation Unit, IRCCS Humanitas Research Hospital, Rozzano-Milan. Italy (M.B., A.B.); Department of Health Sciences, Università del Piemonte Orientale, Novara. Italy (M.B.); and Department of Biomedical Sciences, Humanitas University, Pieve Emanuele-Milan, Italy (A.B.).
Salvatore Facciorusso
Milena Carmela D'Ascanio
Mirko Filippetti
Marco Battaglia
Alessio Baricich
Alessandro Picelli
Andrea Santamato

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeHemiplegic shoulder pain (HSP) represents a common and disabling complication following stroke, which has multiple causes and important functional consequences. Physical modalities are frequently used to manage HSP, but evidence on their effectiveness remains inconsistent. Our aim is to systematically review the evidence from randomized controlled trials (RCTs) on the efficacy and safety of physical modalities, compared with sham or standard care, for improving pain and function in adults with poststroke HSP.

methodsThis systematic review was conducted following the Cochrane Guidelines and Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. We included RCTs assessing physical modalities versus sham or standard therapy in adult stroke survivors with HSP. The primary outcome was pain reduction; secondary outcomes included functional mobility, quality of life, and adverse events. A comprehensive search was conducted in MEDLINE, EMBASE, CENTRAL, PEDro, CINAHL, Web of Science, ClinicalTrials.gov , and World Health Organisation International Clinical Trials Registry Platform (WHO ICTRP) up to July 30, 2025. Risk of bias was assessed using the Cochrane Risk of Bias tool 2.

resultsTwelve RCTs involving 567 participants were included. Interventions comprised electrotherapy (n = 6), shock wave therapy (n = 3), and laser therapy (n = 3). Most studies showed significant pain reduction compared with control. Electrotherapy provided sustained analgesia; extracorporeal shock wave therapy improved structural abnormalities and pain; laser therapy enhanced both pain and functional outcomes. Adverse events were mostly mild. However, safety conclusions are limited by incomplete and inconsistent adverse event reporting. Heterogeneity in interventions and outcomes precluded meta-analysis. DISCUSSION AND

conclusionsBased on low to very low certainty evidence, physical modalities may offer benefit for HSP, but uncertainty remains regarding both long-term effectiveness and safety. Integration into multimodal rehabilitation protocols may be considered.

Indexed as

HemiplegiaPhysical Therapy ModalitiesShoulder PainStrokeStroke RehabilitationHumansRandomized Controlled Trials as TopicTreatment Outcomehemiplegic shoulder painphysical modalitiesstroke rehabilitationsystematic review

Identifiers

PMID42226090
PMCPMC13592833

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.