Evidence map›Paper›PMID 42226070›Full record

ArticleMolecular horticulture2026

Blue light receptor phot2 collaborates with NRL-30 to negatively regulate immunity by reducing mitochondrial protein PRXIIF stability in potato.

Huishan Qiu, Yanli Liu, Tianyu Lin, Dong Cheng, Qingguo Sun, Xinya Wu, Lang Liu, Jiahui Nie, Mingshuo Fan, Jing Zhou and 5 more

Abstract read
In one paragraph

Article in Molecular horticulture, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Huishan QiuNational Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Huazhong Agricultural University (HZAU), Wuhan, 430070, China.
Yanli LiuNational Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Huazhong Agricultural University (HZAU), Wuhan, 430070, China.
Tianyu LinNational Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Huazhong Agricultural University (HZAU), Wuhan, 430070, China.
Dong ChengNational Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Huazhong Agricultural University (HZAU), Wuhan, 430070, China.
Qingguo SunNational Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Huazhong Agricultural University (HZAU), Wuhan, 430070, China.
Xinya WuNational Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Huazhong Agricultural University (HZAU), Wuhan, 430070, China.
Lang LiuNational Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Huazhong Agricultural University (HZAU), Wuhan, 430070, China.
Jiahui NieNational Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Huazhong Agricultural University (HZAU), Wuhan, 430070, China.
Mingshuo FanNational Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Huazhong Agricultural University (HZAU), Wuhan, 430070, China.
Jing ZhouNational Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Huazhong Agricultural University (HZAU), Wuhan, 430070, China.
Ruimin YuNational Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Huazhong Agricultural University (HZAU), Wuhan, 430070, China.
Meng XuNational Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Huazhong Agricultural University (HZAU), Wuhan, 430070, China.
Qin HeNational Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Huazhong Agricultural University (HZAU), Wuhan, 430070, China.
Hongying DuCollege of Light Industry and Food Engineering, Nanjing Forestry University, Nanjing, Jiangsu, China.
Zhendong TianNational Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, Huazhong Agricultural University (HZAU), Wuhan, 430070, China. tianzhd@mail.hzau.edu.cn.ORCID http://orcid.org/0000-0002-3271-5372

Funding

National Natural Science Foundation of China 31761143007National Natural Science Foundation of China 32072121National Natural Science Foundation of China 32072409National Natural Science Foundation of China 32372172
6 · The paper itself

Abstract

Blue light (BL) receptor phototropins (phots) regulate numerous BL-induced physiological responses through NPH3/RPT2-like (NRL) family members. However, how phots and NRL proteins regulate plant immunity remain incompletely understood. This study demonstrates that Stphot2 negatively regulated resistance against Phytophthora infestans, the causal agent of late blight, in potato and Nicotiana benthamiana. Stphot2 interacts with an NRL protein, StNRL-30, which functions as a susceptibility factor. Homodimerization and C-terminal consensus sequence (RxSΦS) of StNRL-30 are essential for accelerating P. infestans infection. The study identifies StNRL-30's interaction with mitochondrial Peroxiredoxin-IIF (StPRXIIF), which positively regulates resistance against P. infestans. StPRXIIF overexpression upregulates mitochondrial alternative oxidase genes and salicylic acid pathway genes, while downregulating jasmonic acid pathway genes. StNRL-30 initiates StPRXIIF degradation, enhanced by Stphot2. In addition, BL treatment promotes StPRXIIF turnover and induces the translocation of the StNRL-30-StPRXIIF complex from the plasma membrane to the chloroplasts. These findings demonstrate how the BL receptor Stphot2, along with StNRL-30, modulates plant immunity by affecting the stability and localization of the positive immunoregulator StPRXIIF, providing insights into BL and plant immunity crosstalk.

Indexed as

Blue light receptorLate blightMitochondrial PRXIIFNPH3/RPT2-like proteinPhototropinP. infestans

Identifiers

PMID42226070
PMCPMC13227800

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.