Evidence map›Paper›PMID 42225928›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2026

Minimally invasive surfactant therapy outcomes in infants born at 28-37 weeks' gestation.

Natasha Ahn, Ilene Wolf, Matthew Derrick

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Article in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Natasha AhnSection of Neonatology, Department of Pediatrics, University of Chicago Medicine Comer Children's Hospital, Chicago, IL, USA. natasha.ahn@uchicagomedicine.org.
Ilene WolfDepartment of Pediatrics, Endeavor Evanston Hospital, Evanston, IL, USA.
Matthew DerrickSection of Neonatology, Department of Pediatrics, University of Chicago Medicine Comer Children's Hospital, Chicago, IL, USA.ORCID http://orcid.org/0009-0009-5542-7240

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveEvaluate whether minimally invasive surfactant therapy (MIST) reduces respiratory support duration in infants born at 28-37 weeks' gestation with respiratory distress syndrome (RDS). STUDY

designRetrospective cohort study of infants with RDS born between 28- 36 6/7 weeks' gestation at a single center level III NICU between 2016-2024. MIST was implemented in 2020. Primary outcome was total days of respiratory support. Secondary outcomes included intubation rates, length of stay, corrected gestational age (cGA) at discharge, and incidence of bronchopulmonary dysplasia (BPD).

resultsOf 218 infants with RDS, the post MIST group had fewer days of respiratory support (8.8 vs 11 days), significantly lower rate of intubation (39% vs 100%), and shorter NICU stay (35.5 vs 41.2 days). BPD among infants <32 weeks' gestation decreased from 43% to 29%.

conclusionMIST was associated with reduced respiratory support and hospitalization duration in this population.

Identifiers

PMID42225928

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.