Evidence map›Paper›PMID 42225898›Full record

ArticleNature neuroscience2026

Why pain biomarkers cannot replace the patient experience.

Jan Vollert, Esther Pogatzki-Zahn, Joletta Belton, Sam Hughes, Luis Garcia-Larrea, Winfried Meissner, Andrew S C Rice, Deidre Ryan, Daniel Segelcke, Katy Vincent and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jan VollertDepartment of Clinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, UK. j.vollert@exeter.ac.uk.ORCID http://orcid.org/0000-0003-0733-5201
Esther Pogatzki-ZahnDepartment of Anaesthesiology, Intensive Care and Pain Medicine, University Hospital Muenster, Muenster, Germany.
Joletta BeltonPain Advocate, Fraser, CO, USA.ORCID http://orcid.org/0000-0001-5174-1691
Sam HughesDepartment of Clinical and Biomedical Sciences, Faculty of Health and Life Sciences, University of Exeter, Exeter, UK.
Luis Garcia-LarreaNeuroPain-Lyon Neurosciences Centre, Inserm U1028 & Univ Claude Bernard, Lyon, France.
Winfried MeissnerJena University Hospital, Department of Anesthesiology and Intensive Care Medicine, Friedrich Schiller University, Jena, Germany.ORCID http://orcid.org/0000-0003-2982-7696
Andrew S C RicePain Research, Department of Surgery and Cancer, Imperial College London, London, UK.
Deidre RyanPain Alliance Europe, Brussels, Belgium.
Daniel SegelckeDepartment of Anaesthesiology, Intensive Care and Pain Medicine, University Hospital Muenster, Muenster, Germany.ORCID http://orcid.org/0000-0002-4405-2596
Katy VincentNuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, UK.
Rolf-Detlef TreedeDepartment of Neurophysiology, Mannheim Center for Translational Neuroscience (MCTN), Mannheim, Germany.
Kai KarosSection Experimental Health Psychology, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, The Netherlands.ORCID http://orcid.org/0000-0001-5905-5725

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID42225898

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.