Evidence map›Paper›PMID 42225881›Full record

ArticleScientific reports2026

The difference between subjective symptoms and objective symptom of edema during the menstrual cycle.

Yuki Takano, Tatuki Shirai, Yudai Tanaka, Kodai Sakamoto, Hirotake Yokota, Ryo Hirabayashi, Tomonobu Ishigaki, Makoto Komiya, Mutsuaki Edama

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuki TakanoInstitute for Human Movement and Medical Sciences, Niigata University of Health and Welfare, Shimami-cho 1398, Kita-ku, Niigata City, 950-3198, Japan.
Tatuki ShiraiInstitute for Human Movement and Medical Sciences, Niigata University of Health and Welfare, Shimami-cho 1398, Kita-ku, Niigata City, 950-3198, Japan.
Yudai TanakaInstitute for Human Movement and Medical Sciences, Niigata University of Health and Welfare, Shimami-cho 1398, Kita-ku, Niigata City, 950-3198, Japan.
Kodai SakamotoInstitute for Human Movement and Medical Sciences, Niigata University of Health and Welfare, Shimami-cho 1398, Kita-ku, Niigata City, 950-3198, Japan.
Hirotake YokotaInstitute for Human Movement and Medical Sciences, Niigata University of Health and Welfare, Shimami-cho 1398, Kita-ku, Niigata City, 950-3198, Japan.
Ryo HirabayashiInstitute for Human Movement and Medical Sciences, Niigata University of Health and Welfare, Shimami-cho 1398, Kita-ku, Niigata City, 950-3198, Japan.
Tomonobu IshigakiInstitute for Human Movement and Medical Sciences, Niigata University of Health and Welfare, Shimami-cho 1398, Kita-ku, Niigata City, 950-3198, Japan.
Makoto KomiyaInstitute for Human Movement and Medical Sciences, Niigata University of Health and Welfare, Shimami-cho 1398, Kita-ku, Niigata City, 950-3198, Japan.
Mutsuaki EdamaInstitute for Human Movement and Medical Sciences, Niigata University of Health and Welfare, Shimami-cho 1398, Kita-ku, Niigata City, 950-3198, Japan. edama@nuhw.ac.jp.ORCID http://orcid.org/0000-0002-2784-6466

Funding

a Grant-in-Aid for Scientific Researchfrom the Japan Society for the Promotion of Science (JSPS) 23H03258)
6 · The paper itself

Abstract

This study aimed to elucidate the differences between subjective and objective symptoms of edema during the menstrual cycle in female university students with regular menstruation. The study included 29 female university students with regular menstrual cycles. The menstrual cycle was categorized into the early follicular, mid-luteal, and late-luteal phases, and measurements were taken during each phase. Subjective symptoms were evaluated using body charts and the Menstrual Distress Questionnaire (MDQ) to assess the presence of edema. Objective symptoms were measured using a body composition analyzer to assess body weight, body water content, and regional water content. In the evaluation of subjective symptoms of edema using the body chart, no significant differences were observed across cycles. However, when body regions were compared, there were significantly fewer subjective symptoms in the upper arm (Rt/Lt) than in the face and trunk across all phases, while the lower leg (Rt/Lt) had significantly more subjective symptoms. The MDQ (water retention item) showed no marked differences across cycles. For objective evaluations of edema, including body weight and total body water, no significant differences were observed across cycles; however, regional water content was significantly higher in the trunk and right arm during the mid-luteal and late-luteal phases than in the early follicular phase. Our findings suggest that the location and timing of subjective edema symptoms may differ from those of objective symptoms.

Indexed as

EdemaMenstrual CycleAdultBody WaterBody WeightFemaleHumansSurveys and QuestionnairesYoung AdultEdemaMenstrual cycleMenstrual distress questionnairePremenstrual syndrome

Identifiers

PMID42225881
PMCPMC13462954

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.