Evidence map›Paper›PMID 42225763›Full record

ArticleScientific reports2026

Nano fountain pen patterning of microtubule tracks for guiding molecular motors.

Orna Fridman, Himanshu Pandey, Mary Popov, Larisa Gheber, Levi A Gheber

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Orna FridmanAvram and Stella Goldstein-Goren Department of Biotechnology Engineering, Ben-Gurion University of the Negev, Be'er-Sheva, Israel.
Himanshu PandeyDepartment of Chemistry, Ben-Gurion University of the Negev, Be'er-Sheva, Israel.
Mary PopovDepartment of Chemistry, Ben-Gurion University of the Negev, Be'er-Sheva, Israel.
Larisa GheberDepartment of Chemistry, Ben-Gurion University of the Negev, Be'er-Sheva, Israel.
Levi A GheberAvram and Stella Goldstein-Goren Department of Biotechnology Engineering, Ben-Gurion University of the Negev, Be'er-Sheva, Israel. glevi@bgu.ac.il.

Funding

Israel Science Foundation 629/23
6 · The paper itself

Abstract

This study explores a new method for transporting biological cargo using motor proteins along their natural tracks, microtubules. Utilizing the nano fountain pen (NFP), we aim to fabricate microtubule pathways connecting designated origin and destination points, offering tracks for kinesin molecules to transport biological cargo. To achieve this, we patterned avidin lines, to which biotinylated microtubules are adhered. The functionality of these immobilized microtubules is confirmed by observing the progressive movement of single kinesin molecules. Furthermore, we demonstrate microtubule alignment through hydrodynamic drag. This method serves as a foundational step toward developing a conveyor network for miniaturized 'lab-on-a-chip' systems, with continued potential for advancements in MT alignment and polarization techniques.

Indexed as

KinesinsMicrotubulesMolecular Motor ProteinsNanotechnologyAnimalsAvidinAvidinKinesinsMolecular Motor Proteins

Identifiers

PMID42225763
PMCPMC13458713

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.