Sensitive determination of breast cancer biomarker, CA 15-3, using a label free electrochemical aptasensor based on palladium nanoparticles decorated carbon nanofibers.

Maryam Nayeri, Seyed Morteza Seifati, Navid Nasirizadeh

Abstract read

In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Maryam NayeriDepartment of Electrical Engineering, Ya.C., Islamic Azad University, Yazd, Iran. maryam.nayeri@iau.ac.ir.

Seyed Morteza SeifatiDepartment of Biology, Medical Biotechnology Research Center, Ashk.C., Islamic Azad University, Ashkezar, Yazd, Iran.

Navid NasirizadehDepartment of Textile and Polymer Engineering, Ya.C., Islamic Azad University, Yazd, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study introduces an electrochemical aptasensor for the sensitive determination of the breast cancer biomarker, carbohydrate antigen 15-3 (CA 15-3). The aptasensor was fabricated by modifying a glassy carbon electrode (GCE) with carbon nanofibers (CNFs) and electrodepositing palladium nanoparticles (PdNPs) on it. CNFs provide a large surface area and active sites for the subsequent electrodeposition of PdNPs. Moreover, PdNPs provide binding sites for attachment of aptamers through coordinate bonds between Pd and amino groups. The fabrication process was monitored using cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). The assay is based on the difference in charge transfer resistance (R

Indexed as

Aptamers, NucleotideBiomarkers, TumorBiosensing TechniquesBreast NeoplasmsElectrochemical TechniquesMetal NanoparticlesMucin-1NanofibersPalladiumCarbonDielectric SpectroscopyFemaleHumansLimit of DetectionAptamers, NucleotideBiomarkers, TumorCarbonMUC1 protein, humanMucin-1PalladiumBreast cancerCA 15-3 biomarkerCarbon nanofibersElectrochemical aptasensorPalladium nanoparticles

Identifiers

PMID42225725

DOI10.1038/s41598-026-52187-2

PMCPMC13457957

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LicenceCC BY-NC-ND

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.