Evidence map›Paper›PMID 42225690›Full record

Trial reportScientific reports2026

Efficacy and safety of photothermal biomodulated platelet-rich plasma versus standard platelet-rich plasma for facial rejuvenation: a prospective split-face randomized study.

Rungsima Wanitphakdeedecha, Ma Patricia Gertrude Camille Rojas Ollero, Woramate Bhorntarakcharoen, Sariya Sittiwanaruk, Wilailuck Phokai, Thanakorn Woramongkol, Thanya Techapichetvanich, Pitchaya Maneeprasopchoke, Panwadee Thongjaroensirikul, Ya-Nin Nokdhes and 2 more

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rungsima WanitphakdeedechaDepartment of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand. rungsima.wan@mahidol.ac.th.ORCID http://orcid.org/0000-0002-3926-2193
Ma Patricia Gertrude Camille Rojas OlleroDepartment of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0009-0003-0467-6454
Woramate BhorntarakcharoenDepartment of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0009-0002-1092-455X
Sariya SittiwanarukDepartment of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0009-0005-5236-4193
Wilailuck PhokaiDepartment of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0009-0000-7446-2038
Thanakorn WoramongkolDepartment of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0009-0009-0148-3490
Thanya TechapichetvanichDepartment of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0000-0001-9590-8887
Pitchaya ManeeprasopchokeDepartment of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Panwadee ThongjaroensirikulDepartment of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0009-0003-5663-4790
Ya-Nin NokdhesDepartment of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.ORCID https://orcid.org/0000-0001-5844-6038
Pornsuk YamlexnoiDepartment of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Onjira MeethongDepartment of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autologous platelet-rich plasma (PRP) regenerative properties are used to treat clinical manifestations of skin aging. This study assessed the efficacy and safety of photothermal biomodulated PRP (PTBM-PRP) compared to standard PRP for skin rejuvenation. Prospective, split-face, randomized study including Thai volunteers (30-60 years) with Fitzpatrick skin type III-IV and moderate severity photoaging or higher conducted at Siriraj Hospital (Bangkok, Thailand). Face sides were randomized to receive intradermal autologous PTBM-PRP or PRP injections in three sessions at one-month intervals, with follow-up visits at one, three, and six months. PRP was preconditioned using the MCT System (Meta Cell Technology, Sant Cugat del Vallès, Spain) preset with the Exosomes program (467 nm continuous light [1 J/cm

Indexed as

Platelet-Rich PlasmaRejuvenationSkin AgingAdultFaceFemaleHumansMaleMiddle AgedProspective StudiesTreatment OutcomeFacial rejuvenationPhotothermal biomodulationPlatelet-rich plasmaPreconditioningWrinkles

Identifiers

PMID42225690
PMCPMC13462578

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.