Evidence map›Paper›PMID 42225358›Full record

ArticleBMJ mental health2026

Predictive analytics to direct clinical attention to complex patients with elevated suicide risk: enhancement of the Veterans Health Administration REACH VET model.

Alina Peluso, Jorge Ramirez Osorio, William H Kazanis, Amy Robinson, Susana B Martins, Hope Cook, Kelley Callaway, Noah Schaefferkoetter, John F McCarthy, Elizabeth M Oliva and 2 more

Abstract read
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Article in BMJ mental health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Alina PelusoOak Ridge National Laboratory, Oak Ridge, TN, USA pelusoa@ornl.gov Jodie.Trafton@va.gov.ORCID http://orcid.org/0000-0003-2895-0406
Jorge Ramirez OsorioOak Ridge National Laboratory, Oak Ridge, TN, USA.
William H KazanisU.S. Department of Veterans Affairs, Palo Alto, CA, USA.
Amy RobinsonU.S. Department of Veterans Affairs, Palo Alto, CA, USA.
Susana B MartinsU.S. Department of Veterans Affairs, Palo Alto, CA, USA.
Hope CookOak Ridge National Laboratory, Oak Ridge, TN, USA.
Kelley CallawayOak Ridge National Laboratory, Oak Ridge, TN, USA.ORCID http://orcid.org/0009-0003-2000-763X
Noah SchaefferkoetterOak Ridge National Laboratory, Oak Ridge, TN, USA.
John F McCarthyU.S. Department of Veterans Affairs, Ann Arbor, MI, USA.
Elizabeth M OlivaU.S. Department of Veterans Affairs, Palo Alto, CA, USA.
Anuj KapadiaOak Ridge National Laboratory, Oak Ridge, TN, USA.
Jodie A TraftonU.S. Department of Veterans Affairs, Palo Alto, CA, USA pelusoa@ornl.gov Jodie.Trafton@va.gov.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSuicide is a major public health concern, particularly among Veterans. The U.S. Department of Veterans Affairs Veterans Health Administration (VHA) employs the Recovery Engagement and Coordination for Health-Veterans Enhanced Treatment (REACH VET) model to prioritise high-risk patients for targeted clinical attention.

objectiveREACH VET 1.0 (RV 1.0) was developed on 2008-2011 data. To reflect changes in clinical practice and populations, VHA updated it to REACH VET 2.0 (RV 2.0). This study describes its development and validation.

methodsRV 2.0 used longitudinal data from 7,248,170 VHA patients (4,967 suicide deaths) in 2018-2019, with 650 time-varying demographic, clinical and area-level predictors derived from a 2-year lookback (2016-2019). An ensemble of Elastic-Net logistic regression models was trained on 2018 data and evaluated monthly at the population level in 2019, focusing on the top 0.1% intervention risk tier. Analyses assessed model discrimination, suicide detection, risk concentration, subgroup consistency (sex, age and race/ethnicity) and performance relative to RV 1.0 using the same percentile-based risk strata.

resultsRV 2.0 outperformed RV 1.0 across all risk strata, with better discrimination (C-statistic 0.76 vs 0.69) and consistent performance across demographic subgroups. Within the top 0.1% of predicted risk, RV 2.0 identified more deaths, higher suicide rates and greater mortality risk concentration both when averaged across the 12 monthly 2019 test sets (5.6 vs 3.6; 83.6 vs 53.7 per 100,000 person-years; 21.0 vs 14.1) and when annualised for 2019 (67 vs 43; 2.7% vs 1.7%; 1,003 vs 644 per 100,000 person-years; 26.7 vs 17.1).

conclusionsRV 2.0 improves suicide risk stratification among Veterans, demonstrating better performance and consistent prediction across subgroups and highlighting the need for regular model updates and evaluation. CLINICAL IMPLICATIONS: RV 2.0 enables targeted interventions and, since its national VHA implementation in June 2025, continues to support system-wide suicide prevention.

Indexed as

SuicideSuicide PreventionVeteransAdultData AnalyticsFemaleHumansLongitudinal StudiesMaleMiddle AgedRisk AssessmentRisk FactorsUnited StatesUnited States Department of Veterans AffairsMental HealthMental Health ServicesPsychiatry

Identifiers

PMID42225358
PMCPMC13239625

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.