Evidence map›Paper›PMID 42224079›Full record

ArticleCell reports2026

Retinal waves shape starburst amacrine cell dendrite development through a direction-selective dendritic computation.

Miah N Pitcher, Aanica S B Gonzales, Raul Habib, Marla B Feller

Abstract read
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In one paragraph

Article in Cell reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Miah N PitcherDepartment of Neuroscience, University of California, Berkeley, Berkeley, CA 94720, USA.
Aanica S B GonzalesDepartment of Neuroscience, University of California, Berkeley, Berkeley, CA 94720, USA.
Raul HabibDepartment of Neuroscience, University of California, Berkeley, Berkeley, CA 94720, USA.
Marla B FellerDepartment of Neuroscience, University of California, Berkeley, Berkeley, CA 94720, USA. Electronic address: mfeller@berkeley.edu.

Funding

UC Berkeley Vision Science COREP30EY003176 · NEI · UNIVERSITY OF CALIFORNIA BERKELEY · PI RICHARD H KRAMER · 1985 to 2026
$16.4M
The Function of Neural Activity in Developing RetinaR01EY013528 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Marla Feller · 2002 to 2026
$8.1M
Development of direction selectivity in the retinaR01EY019498 · NEI · UNIVERSITY OF CALIFORNIA BERKELEY · PI Marla Feller · 2009 to 2026
$6.6M
Investigating Mechanisms of Development in Retinal Direction Selective CircuitsF31EY035571 · NEI · UNIVERSITY OF CALIFORNIA BERKELEY · PI PITCHER, MIAH NIEVA · 2024 to 2025
$92k
NEI NIH HHS F31 EY035571NEI NIH HHS P30 EY003176NEI NIH HHS R01 EY013528NEI NIH HHS R01 EY019498
6 · The paper itself

Abstract

During development, dendrites undergo structural plasticity in response to neural activity; however, whether spatiotemporal activity patterns can instruct dendritic growth remains unclear. Prior to vision, the developing mouse retina exhibits spontaneous retinal waves with a nasal propagation bias that mimics forward optic flow. Here, we reveal that starburst amacrine cells use direction-selective dendritic computations to transform this propagation bias into asymmetric dendrite growth, linking activity patterns to structural development.

Indexed as

Amacrine CellsDendritesRetinaAnimalsMicecircuit maturationCP: neurosciencedendritic compartmentalizationmotion computationoptic flowspatiotemporal integrationspontaneous activitysubcellular signalingvisual system development

Identifiers

PMID42224079
PMCPMC13374506

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.