ArticleRadiological physics and technology2026
Comparison of platinum and gold fiducial markers for prostate radiotherapy: a phantom study.
Article in Radiological physics and technology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Gold fiducial markers (GMs) are widely used in prostate radiotherapy; however, their magnetic susceptibility can reduce visibility on T2-weighted (T2w) MRI and may compromise CT-MRI registration. Using coil-shaped platinum fiducial markers (PMs) and GMs (5 mm in length; diameters 0.35-0.75 mm), we acquired 3 T T2w fast spin-echo MRI in an agar phantom and CT/cone-beam CT (CBCT) in a water-equivalent phantom under clinical settings. MRI visibility was quantified using the signal void area (SVA) and region-of-interest [ROI] value contrast (RVC), and CT/CBCT artifacts were quantified using an artifact index (AI). Additionally, to reflect clinical use, we evaluated CT-referenced registration estimation errors after automatic CT-MRI registration using a phantom containing a registration target. Registration errors were comparable at 0.35 mm, but were significantly smaller for PMs at 0.50 mm and 0.75 mm (p < 0.01). PMs may enable accurate T2w-based CT-MRI registration without increasing CT/CBCT artifacts.
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