Evidence map›Paper›PMID 42223700›Full record

Observational studySupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2026

Acute cancer-related fatigue response following exercise during an outpatient cancer rehabilitation program.

Emma L Gomes, Ryan J Marker, Christopher Bell, Stephen Aichele, Jeff Eagan, Heather J Leach

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Emma L GomesDepartment of Health and Exercise Science, Colorado State University, Fort Collins, CO, USA.ORCID http://orcid.org/0000-0003-2431-9860
Ryan J MarkerDepartment of Physical Medicine and Rehabilitation, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.ORCID http://orcid.org/0000-0003-2795-8502
Christopher BellDepartment of Health and Exercise Science, Colorado State University, Fort Collins, CO, USA.ORCID http://orcid.org/0000-0002-7706-0912
Stephen AicheleDepartment of Human Development and Family Studies, School of Public Health, Colorado State University, Fort Collins, CO, USA.ORCID http://orcid.org/0000-0002-3397-7921
Jeff EaganThe Wellness Place- UC Health Hospital, University of Colorado Health, Fort Collins, CO, USA.
Heather J LeachDepartment of Health and Exercise Science, Colorado State University, Fort Collins, CO, USA. Heather.Leach@colostate.edu.ORCID http://orcid.org/0000-0003-3484-2225

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCancer-related fatigue (CRF) affects the majority of cancer survivors and can negatively impact activities of daily living. Exercise training reduces CRF, but little is known about the immediate or "acute" association of exercise on CRF. This study examined changes in CRF from before to immediately after and several hours following an exercise session, and explored the relationship of exercise intensity.

methodsObservational longitudinal cohort study of cancer survivors enrolled in a 12-week outpatient cancer rehabilitation program. CRF was assessed before, immediately after, and 1-, 4-, and 7-h after one exercise session per week, and at the same clock time on one non-exercise day per week using a visual analog scale (0 = no fatigue, 10 = high fatigue). Exercise sessions consisted of aerobic and resistance training, and intensity was self-selected. Sessions were categorized as either light or moderate based on heart rate and rating of perceived exertion. Mixed effects models with random and fixed effects for time and exercise session intensity evaluated changes in CRF from before to after exercise sessions.

resultsParticipants N = 25 (M = 62 ± 12 years, 84% female, 48% Stage III/IV cancer) completed N = 187 exercise sessions (M = 7.0 ± 3.3). There was no change in CRF from before (3.19 ± 1.61) to immediately after exercise sessions (3.13 ± 1.61) (p = 0.62). CRF significantly increased from the post-exercise to the 7-h time point on both exercise (p = 0.001) and non-exercise days (p < .001). There was an increase in CRF (+ .35) following moderate-to-vigorous exercise sessions compared to a decrease following low-intensity sessions (-.21) (p = 0.02).

conclusionThere was no difference in CRF from before to immediately after exercise sessions, and CRF was highest at the 7-h time-point on both exercise and non-exercise days. These findings suggest that exercise had a minimal association with CRF, and exercise intensity was not related to this change in CRF.

Indexed as

ExerciseExercise TherapyFatigueNeoplasmsActivities of Daily LivingAgedCohort StudiesFemaleHeart RateHumansLongitudinal StudiesMaleMiddle AgedOutpatientsResistance TrainingTime FactorsAcuteCancer-related fatigueCancer survivorsExerciseOutpatient

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.