ArticleAntonie van Leeuwenhoek2026
A bioactive pigment from violet-hued bacteria: a dual approach against prostate cancer and bacterial infections.
Article in Antonie van Leeuwenhoek, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
Given the high potential of microbial metabolites, including pigments, and the desire to utilize them in pharmaceuticals, we decided to isolate the violacein pigment from its producing bacteria and investigate its antioxidant, antimicrobial, and anticancer properties in a PC3 cell line. The bacterium that produces the violacein pigment was isolated from the soil and identified through 16S rRNA sequencing. The pigment was extracted using absolute ethanol. After confirming the pigment, its antimicrobial, antioxidant, and anticancer activities were evaluated using MTT, flow cytometry with apoptosis and cell cycle assays in the PC3 cell line. The violacein-producing bacterium has been identified and named Janthinobacterium lividum strain BAH 1. This pigment was found to have a more significant effect on Gram-positive bacteria; specifically, its highest impact, at a concentration of 1 mg mL
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