ReviewResults and problems in cell differentiation2026
Setting Up to Divide: Nuclear Mechanotransduction in the Regulation of Mitosis.
Review in Results and problems in cell differentiation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
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Authors and funding
1 author.
Funding
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Abstract
As the largest and stiffest cellular organelle, the nucleus is continuously under the influence of mechanical forces from external and internal sources. These forces trigger an adaptive response at the nuclear level that include changes in nucleocytoplasmic transport, chromatin architecture, or transcriptional activity, ultimately driving cell proliferation or differentiation. In preparation for mitosis, nuclear structure and organization is modified to ensure that chromosomes are efficiently captured and correctly separated. How these modifications impact the mechanical response of the nucleus remains a largely unexplored area. One emerging concept is that changes in the mechanical properties of the nucleus during early mitosis are required to ensure the timing and accuracy of chromosome segregation. This review will discuss the contribution of key nuclear components to nuclear mechanics and their relevance for chromosome segregation fidelity.
Indexed as
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42223640What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.