Evidence map›Paper›PMID 42223635›Full record

ReviewResults and problems in cell differentiation2026

Podosomes and Mechanical Force.

Malgorzata Kloc, Souhail A Thabet, Samruddhi Ranmale, Jarek Wosik

Abstract readReview
PubMed Publisher
In one paragraph

Review in Results and problems in cell differentiation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Malgorzata KlocThe Houston Methodist Research Institute, Transplant Immunology, Houston, TX, USA. mkloc@houstonmethodist.org.ORCID https://orcid.org/0000-0002-5192-8584
Souhail A ThabetThe Houston Methodist Hospital, Department of Surgery, Houston, TX, USA.
Samruddhi RanmaleThe Houston Methodist Research Institute, Transplant Immunology, Houston, TX, USA.
Jarek WosikElectrical and Computer Engineering Department, University of Houston, Houston, TX, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Podosomes are specialized, highly dynamic adhesion structures protruding from the membrane of animal cells. Their complex ultrastructure enables interactions with the microenvironment and extracellular matrix and the sensory and mechano-effector functions. Although historically attributed to monocytes, macrophages, and dendric cells, podosomes also occur in osteoclasts, endothelial cells, muscle, neural, cancer, and other cell types. This review describes podosome structure and podosomes' role in mechanotransduction and beyond.

Indexed as

Mechanotransduction, CellularPodosomesAnimalsExtracellular MatrixHumansOsteoclastsActin cytoskeletonInvadopodiumMechanical forceMechanotransductionPodosome

Identifiers

PMID42223635

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.